The effect of haemorrhage on hepatic artery and portal vein flows in the anaesthetized cat

1. In cats anaesthetized with pentobarbitone, the hepatic artery and portal vein flows and pressures were recorded simultaneously. 2. Removal of blood from the animal did not cause a decrease in the hepatic artery flow unless the arterial pressure fell below 80 mm Hg. In contrast, the portal vein fl...

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Published inThe Journal of physiology Vol. 193; no. 2; pp. 375 - 379
Main Authors Greenway, C. V., Lawson, Anne E., Stark, R. D.
Format Journal Article
LanguageEnglish
Published England The Physiological Society 01.11.1967
Subjects
Animals
Blood Flow Velocity
Blood Pressure - drug effects
Blood Pressure Determination
Cats
Hemorrhage - physiopathology
Hepatic Artery - physiopathology
Histamine - pharmacology
Portal System - physiopathology
Regional Blood Flow
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Summary:1. In cats anaesthetized with pentobarbitone, the hepatic artery and portal vein flows and pressures were recorded simultaneously. 2. Removal of blood from the animal did not cause a decrease in the hepatic artery flow unless the arterial pressure fell below 80 mm Hg. In contrast, the portal vein flow fell markedly. 3. After restoration of the blood, the hepatic artery flow increased to above the pre-haemorrhage level, while portal vein flow returned only partly towards the control level. 4. It is concluded that haemorrhage causes a vasodilation in the hepatic artery vascular bed and a vasoconstriction in the vascular beds drained by the portal vein. By this means, the oxygen supply to the liver is maintained as far as possible.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-3751
1469-7793
DOI:10.1113/jphysiol.1967.sp008363