Chemistry, Sustainability and Naturality of Perfumery Biotech Ingredients

• Published in: ChemSusChem Vol. 13; no. 21; pp. 5600 - 5610
• Main Authors: Lecourt, Mathilde, Antoniotti, Sylvain
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 06.11.2020; ChemPubSoc Europe/Wiley
• Subjects: Analytical chemistry; biocatalysis; Biosynthesis; Catalysis; Chemical composition; Chemical Sciences; Chemistry; Cloning; Essential oils; fragrance; green chemistry; Ingredients; metabolic engineering; Metabolism; Optimization; Organic chemistry; Patent applications; Scientific papers; Sustainability; Sustainable materials; fragrance; metabolic engineering; green chemistry; sustainability; biocatalysis
• ISSN: 1864-5631; 1864-564X; 1864-564X
• DOI: 10.1002/cssc.202001661

White biotechnology has emerged in biochemical manufacturing processes to deliver perfumery ingredients satisfying interests of the society for natural, eco‐responsible, and sustainable materials. As a result, an intense R&D activity has taken place on these subjects, resulting in both scientific publications and patent applications reporting combinations of state‐of‐the‐art approaches in biocatalysis, metabolic engineering, synthetic biology, biosynthesis elucidation, gene edition and cloning, and analytical chemistry. In this Minireview, a smelly selection of novel biotechnological processes and ingredients from a scientific articles and patents survey covering the last 6 years is presented and analysed in terms of chemistry, sustainability and naturality. Classification has been made between metabolic engineering on one side, allowing either biotechnological synthesis of essential oil surrogates or single molecule ingredients, and on the other side the optimisation of properties of natural complex substances by specific and selective enzymatic modifications of their chemical composition. The scent of sustainability: White biotechnology has emerged in manufacturing processes to deliver perfumery ingredients satisfying novel interests of the society for natural, eco‐responsible, and sustainable materials. In this Minireview, we present a selection of novel biotechnological processes and ingredients encompassing combinations of state‐of‐the‐art approaches in biocatalysis, metabolic engineering, synthetic biology, biosynthesis elucidation, gene edition and cloning, and analytical chemistry.