The Neural Mechanism by Which the Dorsal Vagal Complex Mediates the Regulation of the Gastric Motility by Weishu (RN12) and Zhongwan (BL21) Stimulation

A large number of studies have been conducted to explore the mechanism of Back-Shu and Front-Mu points. While several lines of evidence addressed the acupuncture information of Shu acupoints and Mu acupoints gathering in the spinal cord, whether the convergence is extended to the high centre still r...

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Published inEvidence-based complementary and alternative medicine Vol. 2013; no. 2013; pp. 1 - 7
Main Authors Wang, Hao, Shen, Guo-ming, Liu, Wei-jian, Huang, Shun, Zhang, Meng-ting
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Puplishing Corporation 01.01.2013
Hindawi Publishing Corporation
Hindawi Limited
Subjects
Abdomen
Acupuncture
Brain
Chinese medicine
Electroacupuncture
Electrophysiology
Gastric motility
Gastroenterology
Laboratory animals
Motility
Peptides
Physiology
Rodents
Software
Spinal cord
Stimulation
Stomach
Vagus nerve
China
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Summary:A large number of studies have been conducted to explore the mechanism of Back-Shu and Front-Mu points. While several lines of evidence addressed the acupuncture information of Shu acupoints and Mu acupoints gathering in the spinal cord, whether the convergence is extended to the high centre still remains unclear. The study selected gastric Mu points (RN12) and gastric Shu points (BL21) regulating gastric motility and its central neural mechanisms as the breakthrough point, using the technique of immunochemistry, nuclei lesion, electrophysiology, and nerve transection. Here, we report that gastric motility regulation of gastric Shu and Mu acupoints and their synergistic effect and the signals induced by electroacupuncture (EA) stimulation of acupoints RN12 and RN12 gather in the dorsal vagal complex (DVC), increasing the levels of gastrointestinal hormones in the DVC to regulate gastric motility through the vagus. In sum, our data demonstrate an important role of DVC and vagus in the regulation of gastric motility by EA at gastric Shu and Mu points.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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Academic Editor: Chang Gue Son
ISSN:1741-427X
1741-4288
DOI:10.1155/2013/291764