Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice

• Published in: Molecular plant Vol. 12; no. 8; pp. 1060 - 1074
• Main Authors: Ruan, Wenyuan, Guo, Meina, Wang, Xueqing, Guo, Zhenhui, Xu, Zhuang, Xu, Lei, Zhao, Hongyu, Sun, Haiji, Yan, Chengqi, Yi, Keke
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 05.08.2019
• Subjects: cytoplasm; enzyme activity; eukaryotic cells; Gene Expression Regulation, Plant - genetics; Homeostasis; loss-of-function mutation; lysine; mutants; Oryza - genetics; phosphate regulation network; phosphates; PHR2; Pi homeostasis; Pi signaling; Plant Proteins - genetics; Plant Proteins - metabolism; rice; SPX4; two hybrid system techniques; ubiquitin; ubiquitin-protein ligase; Ubiquitin-Protein Ligases - genetics; Ubiquitin-Protein Ligases - metabolism; ubiquitination; Ubiquitination - genetics; Ubiquitination - physiology; ubiquitination; Pi signaling; Pi homeostasis; phosphate regulation network; rice; PHR2; SPX4

SPX-domain-containing proteins (SPXs) play an important role in inorganic phosphate (Pi) sensing, signaling, and transport in eukaryotes. In plants, SPXs are known to integrate cellular Pi status and negatively regulate the activity of Pi central regulators, the PHOSPATE STARVATION RESPONSE proteins...