Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis

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Published inJournal of Bacteriology Vol. 181; no. 18; pp. 5600 - 5605
Main Authors Vrijbloed, J W, Zerbe-Burkhardt, K, Ratnatilleke, A, Grubelnik-Leiser, A, Robinson, J A
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.09.1999
Subjects
Antibiotics
Bacterial Proteins
Bacteriology
Carbon Isotopes
Drug Resistance, Microbial - genetics
Enzymes
Genetics
Genetics and Molecular Biology
insertional inactivation
isobutyryl-CoA mutase
Isomerases - genetics
Isomerases - metabolism
Macromolecular Substances
methylmalonyl-CoA mutase
Methylmalonyl-CoA Mutase - genetics
Methylmalonyl-CoA Mutase - metabolism
Monensin - biosynthesis
Monensin - chemistry
Mutagenesis, Insertional
Mutation
Phenotype
polyketide antibiotics
Streptomyces - enzymology
Streptomyces - genetics
Streptomyces - growth & development
Streptomyces cinnamonensis
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Summary:Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JB About JB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0021-9193 Online ISSN: 1098-5530 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to JB .asm.org, visit: JB       
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content type line 23
Corresponding author. Mailing address: Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland. Phone: (0041)-1-635-4242. Fax: (0041)-1-635-6812. E-mail: robinson@oci.unizh.ch.
ISSN:0021-9193
1067-8832
1098-5530
DOI:10.1128/JB.181.18.5600-5605.1999