Primary tumor prevalence has an impact on the constituent ratio of metastases to the jaw but not on metastatic： sites

• Published in: International journal of oral science Vol. 3; no. 3; pp. 141 - 152
• Main Authors: Zhang, Fu‐gui, Hua, Cheng‐ge, Shen, Mo‐lun, Tang, Xiu‐fa
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2011; Springer Nature B.V; State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China%Department of Head and Neck Oncology, West China School of Stomatology, Sichuan University, Chengdu 610041, China%Department of Stomatology, The Second People's Hospital of Hefei, Hefei 230011, China; Nature Publishing Group
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms - pathology; Chi-Square Distribution; Child; Child, Preschool; Dentistry; Female; Humans; Infant; Jaw Neoplasms - mortality; Jaw Neoplasms - secondary; Jaw Neoplasms - therapy; Kidney Neoplasms - pathology; Liver Neoplasms - pathology; Lung Neoplasms - pathology; Male; Medicine; Middle Aged; Neoplasm Metastasis - physiopathology; Oral and Maxillofacial Surgery; Original; original-article; Orthopedics; Palliative Care; Prognosis; Prostatic Neoplasms - pathology; PTP; Statistics, Nonparametric; Surgical Orthopedics; Survival Analysis; Thyroid Neoplasms - pathology; Young Adult; 临床特征; 前列腺癌; 患病率; 统计分析; 网站; 肿瘤细胞; 转移性; metastases; jaws; tumor; tumor,metastases
• ISSN: 1674-2818; 2049-3169
• DOI: 10.4248/IJOS11052

This article provides an overview of metastases to jaws （M J）, mainly concerning the differences between American and Chinese patients, and exploring the relationship between the primary tumors＇ prevalence （PTP） and constituent ratio of MJ. Information concerning of 399 MJ cases in 215 papers, including one new case in our hospital, was subjected to statistic analysis. The main clinical features of M J, such as constituent ratio of PTP and that of M J, metastatic sites, treatments, and prognosis were summarized. Breast, lung, kidney, prostate and thyroid （in descending order） were the leading primary sites of MJ. Furthermore, the constituent ratio of MJ was found to be correlated with that of PTP in all subjects including American and Chinese subjects in our study. As to metastatic sites in the mandible, a specific ＂M＂ shaped pattern appeared regardless of the tumor type or constituent ratio,,; of MJ were in all subjects. Almost all subjects received traditionary palliative treatments, and the prognosis was quite poor. The PTP had a significant impact on the constituent ratio of MJ. However, it was the properties of the microenvironment rather than characteristics or constituent ratios of tumor cells, that decided the metastatic sites in various tumor subjects.