A case of Turner’s syndrome with Graves’ disease and primary hyperparathyroidism

We report a 21-year-old woman with Turner’s syndrome, Graves’ disease and primary hyperparathyroidism. At 12 years of age, she was of short stature, and was diagnosed with Turner’s syndrome and treated with growth hormone. At the age of 17 years, she was diagnosed with Graves’ disease. On treatment...

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Bibliographic Details
Published inSAGE open medical case reports Vol. 9; p. 2050313X211059002
Main Authors Nagaki, Shigeru, Tachikawa, Emiko, Kodama, Hitomi, Obara, Takao, Osawa, Makiko, Nagata, Satoru
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.11.2021
Sage Publications Ltd
SAGE Publishing
Subjects
Case Report
Case reports
Laboratories
Neuroendocrine tumors
Tumors
Short stature
Turner’s syndrome
primary hyperparathyroidism
Graves’ disease
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Summary:We report a 21-year-old woman with Turner’s syndrome, Graves’ disease and primary hyperparathyroidism. At 12 years of age, she was of short stature, and was diagnosed with Turner’s syndrome and treated with growth hormone. At the age of 17 years, she was diagnosed with Graves’ disease. On treatment with methimazole, her laboratory findings normalized. At the age of 20 years, her serum calcium and intact parathyroid hormone levels were high. The upper left parathyroid gland showed swelling and was resected, and adenoma was diagnosed pathologically. Then, primary hyperparathyroidism induced by the adenoma was diagnosed. After the parathyroidectomy, the patient’s serum calcium and intact parathyroid hormone levels normalized. Is likely that Turner’s syndrome and Graves’ disease were not associated with primary hyperparathyroidism. Multiple endocrine neoplasia type 1 was unlikely considering the clinical, laboratory, ultrasonographic, and scintigraphic findings.
ISSN:2050-313X
2050-313X
DOI:10.1177/2050313X211059002