Changes in movement-related β-band EEG signals in human spinal cord injury

• Published in: Clinical neurophysiology Vol. 121; no. 12; pp. 2017 - 2023
• Main Authors: Gourab, Krishnaj, Schmit, Brian D
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ireland Ltd 01.12.2010; Elsevier
• Subjects: Acoustic Stimulation - methods; Analysis of Variance; Behavioral psychophysiology; Beta Rhythm; Biological and medical sciences; Brain Mapping; EEG; Electrodiagnosis. Electric activity recording; Electromyography - methods; Electrophysiology; Event related synchronization; Event-related desynchronization; Evoked Potentials - physiology; Fundamental and applied biological sciences. Psychology; Humans; Investigative techniques, diagnostic techniques (general aspects); Linear Models; Medical sciences; Movement; Movement - physiology; Nervous system; Neurology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Spinal Cord Injuries - diagnosis; Spinal Cord Injuries - physiopathology; Spinal cord injury; Time Factors; β-band; β-band; Event-related desynchronization; Movement; Event related synchronization; Spinal cord injury; EEG; Central nervous system; Electrophysiology; Electroencephalography; Encephalon; Brain-computer interface; Electrodiagnosis; Frequency band; Topography; Spinal cord trauma; Desynchronization; Human; Nervous system diseases; Toe; Pattern recognition; Synchronization; Chronic; p-band; Central nervous system disease; Sensory disorder; Spinal cord disease
• ISSN: 1388-2457; 1872-8952; 1872-8952
• DOI: 10.1016/j.clinph.2010.05.012

The purpose of this study was to characterize differences in movement-related β-band signals of the brain between people with chronic spinal cord injury (SCI) and neurologically intact volunteers. A 64 channel EEG system was used to record EEG while subjects attempted brisk toe plantar flexion in response to auditory cues. Change in amplitude in β-band frequencies during times of event-related desynchronization and synchronization (ERD and ERS) and topography of ERD and ERS were compared across groups and correlated to ASIA motor and sensory impairment scores for SCI subjects. ERS amplitude immediately following the movement attempt was significantly smaller ( t-test; p < 0.001 ) in SCI subjects as compared to controls. The ERD change tended to be greater and the topography was more widespread in SCI subjects. Incomplete SCI subjects with more severe neurological injury (lesser ASIA motor score) had lower peak ERS amplitude and a significant correlation was observed between sensorimotor impairments and ERS amplitude (r 2 = 0.79; p = 0.02 ). Our results suggest that motor processing in the brain is altered after SCI, and that it occurs in proportion to the severity of neurological injury. These results are important for brain computer interface applications that rely on ERD and ERS pattern recognition.