Treatment of primary hepatic carcinoma through ultrasound-guided microwave ablation

• Published in: Nigerian journal of clinical practice Vol. 22; no. 10; pp. 1408 - 1411
• Main Authors: Fang, L, Meng, X, Luo, W, Zhou, X
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.10.2019; Medknow Publications and Media Pvt. Ltd
• Subjects: Ablation (Surgery); Ablation Techniques; Adult; Alanine Transaminase - blood; Aspartate Aminotransferases - blood; Blood transfusion; Cancer; Carcinoma; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - surgery; Care and treatment; Female; Hepatocellular carcinoma; Humans; Laparotomy - methods; Length of Stay; Liver diseases; Liver Neoplasms - pathology; Liver Neoplasms - surgery; Male; Medical research; Microwaves - therapeutic use; Middle Aged; Prothrombin; Radiofrequency Ablation - methods; Sorafenib; Surgery; Treatment Outcome; ultrasound guidance; Microwave ablation; primary hepatic carcinoma
• ISSN: 1119-3077
• DOI: 10.4103/njcp.njcp_368_18

Objective: To study the clinical effect of ultrasound-guided microwave ablation on primary hepatic carcinoma. Method: The subjects comprised 94 patients with primary hepatic carcinoma who were admitted to our hospital between August 2014 and November 2016. They were divided into two groups in accordance with a random-number table. The control (n = 47) and study (n = 47) groups received conventional surgical excision and ultrasound-guided microwave ablation, respectively. The operation duration, clinical effect, complication occurrence rates, and hepatic functions of the two groups were compared. Results: The control group exhibited longer duration of operation and length of stay but significantly lower quantities of intraoperative bleeding and blood transfusion (P < 0.05) than the study group. The study group demonstrated significantly higher (P < 0.05) effective rate of treatment but significantly lower (P < 0.05) occurrence rate of complications than the control group. The study group exhibited significantly higher (P < 0.05) albumin and total bilirubin levels but significantly lower alanine aminotransferase and aspartate transaminase levels than the control group. No difference was observed in prothrombin time between the two groups (P > 0.05). Conclusion: Ultrasound-guided microwave ablation treatment offers the advantages of minor injury and low complication occurrence rates. Moreover, it is associated with faster postoperative recovery and improved hepatic function. Thus, it is worthy as a clinical option and must be promoted and applied.