TCM2COVID: A resource of anti‐COVID‐19 traditional Chinese medicine with effects and mechanisms

• Published in: iMeta Vol. 1; no. 4; pp. e42 - n/a
• Main Authors: Ren, Liping, Xu, Yi, Ning, Lin, Pan, Xianrun, Li, Yuchen, Zhao, Qi, Pang, Bo, Huang, Jian, Deng, Kejun, Zhang, Yang
• Format: Journal Article
• Language: English
• Published: Australia John Wiley & Sons, Inc 01.12.2022; John Wiley and Sons Inc; Wiley
• Subjects: Chinese medicine; Clinical trials; Coronaviruses; COVID-19; Drug dosages; herb; Herbs; natural product; Recipes; traditional Chinese medicine; China; traditional Chinese medicine; database; COVID‐19; herb; natural product
• ISSN: 2770-596X; 2770-5986; 2770-596X
• DOI: 10.1002/imt2.42

In China, traditional Chinese medicine (TCM) has been widely used for coronavirus infectious disease 2019 (COVID‐19) prevention, treatment, and recovery and has played a part in the battle against the disease. A variety of TCM treatments have been recommended for different stages of COVID‐19. But, to the best of our knowledge, a comprehensive database for storing and organizing anti‐COVID TCM treatments is still lacking. Herein, we developed TCM2COVID, a manually curated resource of anti‐COVID TCM formulas, natural products (NPs), and herbs. The current version of TCM2COVID (1) documents over 280 TCM formulas (including over 300 herbs) with detailed clinical evidence and therapeutic mechanism information; (2) records over 80 NPs with detailed potential therapeutic mechanisms; and (3) launches a useful web server for querying, analyzing and visualizing documented formulas similar to those supplied by the user (formula similarity analysis). In summary, TCM2COVD provides a user‐friendly and practical platform for documenting, querying, and browsing anti‐COVID TCM treatments, and will help in the development and elucidation of the mechanisms of action of new anti‐COVID TCM therapies to support the fight against the COVID‐19 epidemic. TCM2COVID is freely available at http://zhangy-lab.cn/tcm2covid/. TCM2COVID documents over 280 traditional Chinese medicine formulas (including over 300 herbs) with detailed clinical evidence and therapeutic mechanism information; TCM2COVID records over 80 natural products with detailed potential therapeutic mechanisms; TCM2COVID launches a useful web server for querying, analyzing, and visualizing documented formulas similar to those supplied by the user (formula similarity analysis). Highlights TCM2COVID documents over 280 TCM formulas (including over 300 herbs) with detailed clinical evidence and therapeutic mechanism information. TCM2COVID records over 80 NPs with detailed potential therapeutic mechanisms. TCM2COVID launches a useful web server for querying, analyzing, and visualizing documented formulas similar to those supplied by the user (formula similarity analysis).