Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter

• Published in: International journal of pharmaceutics: X Vol. 3; p. 100094
• Main Authors: Vreeman, Gerrit, Sun, Changquan Calvin
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2021; Elsevier
• Subjects: Compaction; Heckel analysis; In-die; Plasticity; Powder; Research Paper; Compaction; In-die; Heckel analysis; Powder; Plasticity

Despite the ability to characterize the plasticity of powders in a material-sparing and expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to several factors, such as particle elastic deformation, tooling size, lubrication, and speed. Using materials exhibiti...