Time trends of perfluoroalkyl substances in blood in 30-year old Norwegian men and women in the period 1986–2007

• Published in: Environmental science and pollution research international Vol. 28; no. 32; pp. 43897 - 43907
• Main Authors: Berg, Vivian, Sandanger, Torkjel Manning, Hanssen, Linda, Rylander, Charlotta, Nøst, Therese Haugdahl
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2021; Springer Nature B.V; Springer
• Subjects: Adult; Alkanesulfonic Acids; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Biological Monitoring; Biomonitoring; Blood; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental Pollutants; Environmental science; Exposure; Female; Fluorocarbons; Humans; Longitudinal Studies; Male; Matematikk og Naturvitenskap: 400; Mathematics and natural science: 400; Medical disciplines: 700; Medisinske Fag: 700; Perfluoroalkyl & polyfluoroalkyl substances; Perfluorochemicals; Pregnancy; Prenatal experience; Prenatal exposure; Research Article; Time; Trends; VDP; Waste Water Technology; Water Management; Water Pollution Control; Women; Study design; Biomonitoring; Blood concentrations; Reproductive ages; Time trends; Exposure; PFAS
• ISSN: 0944-1344; 1614-7499; 1614-7499
• DOI: 10.1007/s11356-021-13809-6

Biomonitoring studies are helpful tools and can increase our knowledge on time trends in human blood concentrations of PFASs: how they relate to emission trends and the potential prenatal exposure for future generations. In this study, serum was sampled in cross-sections of men and women who were 30 years old in each of the years 1986, 1994, 2001, and 2007 in Northern Norway and analyzed for 23 PFASs. Differences in serum concentrations across sampling years were investigated graphically and with significance testing and compared with those observed in our previous longitudinal study using repeated individual measurements in older men in the same years. The results demonstrate overall increasing blood burdens of PFASs in men and women in reproductively active ages during 1986–2001 and decreases until 2007. However, longer chained PFASs were still increasing in 2007 indicating divergent time trends between the different PFASs, underlining the importance of continued biomonitoring. Comparisons between 30-year-old men and older men within the same population demonstrated variation in time trends in the exact same years, underlining that biomonitoring studies must regard historic exposures and birth cohort effects.