Low serum testosterone concentrations in hospitalized men with poorly controlled type 2 diabetes

• Published in: Endocrinology and metabolism (Seoul) Vol. 29; no. 4; pp. 574 - 578
• Main Authors: Kim, Kyung Soo, Kang, San Ha, Kim, Moon Jong, Kim, Soo Kyung, Kim, Yoo Lee, Park, Won Keun, Park, Seok Won, Cho, Yong Wook
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Endocrine Society 01.12.2014; 대한내분비학회
• Subjects: Brief Report; Diabetes mellitus, type 2; Hypogonadism; Testosterone; 내과학; Diabetes mellitus, type 2; Testosterone; Hypogonadism
• ISSN: 2093-596X; 2093-5978
• DOI: 10.3803/EnM.2014.29.4.574

Our aim was to examine whether serum testosterone concentrations are in fact low in hospitalized men with poorly controlled type 2 diabetes compared with healthy men. In this study, 79 men aged 40 years or older (41 healthy men and 38 men with type 2 diabetes) were included. Total testosterone and sex hormone-binding globulin levels were measured. The average duration of diagnosed diabetes was 10.8 years and the mean glycated hemoglobin value was 10.8%. Total testosterone concentrations were lower in men with type 2 diabetes than in healthy men, after adjusting for age and body mass index (3.83±0.32 ng/mL vs. 5.63±0.31 ng/mL, P<0.001). In conclusion, this study shows that serum testosterone concentrations are lower in hospitalized men with poorly controlled type 2 diabetes than in healthy men. Therefore, men with poorly controlled type 2 diabetes should undergo further assessment for hypogonadism.