Non-specific effects of methylphenidate (Ritalin) on cognitive ability and decision-making of ADHD and healthy adults

• Published in: Psychopharmacologia Vol. 210; no. 4; pp. 511 - 519
• Main Authors: Agay, Nirit, Yechiam, Eldad, Carmel, Ziv, Levkovitz, Yechiel
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.07.2010; Springer; Springer Nature B.V
• Subjects: Adult; Adult and adolescent clinical studies; Attention Deficit Disorder with Hyperactivity - psychology; Attention deficit hyperactivity disorder; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cognition - drug effects; Cognitive ability; Comparative studies; Decision making; Decision Making - drug effects; Double-Blind Method; Female; Humans; Intellectual deficiency; Male; Medical sciences; Methylphenidate - pharmacology; Middle Aged; Neuropharmacology; Neurosciences; Original Investigation; Pharmacology; Pharmacology. Drug treatments; Pharmacology/Toxicology; Placebos; Psychiatry; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease); Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Decision-making; Developmental disorder; Behavioral assessment; Memory; Attention; Human; Healthy subject; CNS stimulant; Decision making; Psychotropic; Cognitive ability; Mental retardation; Behavioral analysis; Piperidine derivatives; Intellectual deficiency; Adult; Attention disorder with hyperactivity; Methylphenidate

Introduction The effect of a single dose of methylphenidate (MPH) on cognitive measures and decision-making processes was assessed in a sample of adults with ADHD and in a control sample. Methods Thirty-two adults satisfying DSM-IV criteria for ADHD and 26 healthy controls performed several cognitiv...