Prospective memory deficits in subjects with schizophrenia spectrum disorders: A comparison study with schizophrenic subjects, psychometrically defined schizotypal subjects, and healthy controls

Memory impairment is one of the core deficits in schizophrenia. This study explored the memory profiles of schizophrenic and psychometrically defined schizotypal subjects. The study participants included 15 patients with schizophrenia, 41 schizotypal subjects, and 20 healthy controls. All of the par...

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Bibliographic Details
Published inSchizophrenia research Vol. 106; no. 1; pp. 70 - 80
Main Authors Wang, Ya, Chan, Raymond C.K., Xin Yu, Shi, Chuan, Cui, Jifang, Deng, Yongyu
Format Journal Article Conference Proceeding
LanguageEnglish
Published Amsterdam Elsevier B.V 01.11.2008
Elsevier
Subjects
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Endophenotype
Female
Health Status
Humans
Male
Medical sciences
Memory
Memory Disorders - diagnosis
Memory Disorders - epidemiology
Neuropsychological Tests
Personality disorders
Phenotype
Prospective memory
Psychiatric/Mental Health
Psychology. Psychoanalysis. Psychiatry
Psychometrics - methods
Psychopathology. Psychiatry
Psychoses
Schizophrenia
Schizophrenia - epidemiology
Schizotypal
Schizotypal Personality Disorder - epidemiology
Semantics
Severity of Illness Index
Time Perception
Verbal Behavior
Visual Perception
Schizophrenia
Prospective memory
Schizotypal
Memory
Endophenotype
Human
Memory disorder
Cognitive disorder
Psychometrics
Cognition
Personality disorder
Psychosis
Schizotypal personality
Comparative study
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ISSN0920-9964
1573-2509
DOI10.1016/j.schres.2007.07.020

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Summary:Memory impairment is one of the core deficits in schizophrenia. This study explored the memory profiles of schizophrenic and psychometrically defined schizotypal subjects. The study participants included 15 patients with schizophrenia, 41 schizotypal subjects, and 20 healthy controls. All of the participants completed verbal and visual memory, working memory, and prospective memory tasks. The results showed that patients with schizophrenia were impaired in all aspects of memory function, whereas the schizotypal subjects tended to show moderate to large impairment effect sizes in prospective memory. It is suggested that prospective memory be considered a potential endophenotype of schizophrenia.
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ISSN:0920-9964
1573-2509
DOI:10.1016/j.schres.2007.07.020