Antibacterial Effect of Allium ampeloprasum and Allium porrum Extracts on Staphylococcus aureus and Pseudomonas aeruginosa

• Published in: Journal of pharmacopuncture Vol. 26; no. 1; pp. 53 - 59
• Main Authors: Gavanji, Shahin, Bakhtari, Azizollah, Baghshahi, Hojjat, Chamgordani, Zahra Hamami, Sadeghi, Akram
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Pharmacopuncture Institute (KPI) 31.03.2023; Korean Pharmacopuncture Institute; 대한약침학회
• Subjects: antibiotic resistance; leek; Original; phytotherapy; pseudomonas aeruginosa; staphylococcus aureus; traditional persian medicine; 한의학; traditional persian medicine; pseudomonas aeruginosa; antibiotic resistance; leek; phytotherapy; staphylococcus aureus
• ISSN: 2093-6966; 2234-6856
• DOI: 10.3831/KPI.2023.26.1.53

The most prominent microorganisms that cause hospital infections and acquire antibiotic resistance are and . The present study aimed to compare the phenolic and flavonoid compounds of various and extracts and evaluate the antibacterial effects of these extracts against these two microorganisms. The total phenolic and flavonoid contents of the acetone, methanol, aqueous, and hexane leeks extracts from and were measured. The antibacterial activity of these extracts against and was tested using the disk diffusion method for 24, 48, and 72 hours. Further, the minimum inhibitory concentrations and the minimum bactericidal concentrations of these extracts for these two bacteria were evaluated and compared with those of common antibiotics. The aqueous extracts showed the highest phenolic and flavonoid contents and at concentrations of 35 and 40 mg per disk, showed the most antibacterial activity against and ; showed more sensitivity to the aqueous extracts than . Aqueous and extracts may prevent the growth of hospital pathogens, especially ; our findings will aid the discovery of new antimicrobial substances against antibiotic-resistant bacteria.