Development of a fully implantable wireless pressure monitoring system

• Published in: Biomedical microdevices Vol. 11; no. 1; pp. 259 - 264
• Main Authors: Tan, Robert, McClure, Timothy, Lin, C. K., Jea, David, Dabiri, Foad, Massey, Tammara, Sarrafzadeh, Majid, Srivastava, Mani, Montemagno, C. D., Schulam, Peter, Schmidt, Jacob
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.02.2009; Springer Nature B.V
• Subjects: Animals; Biological and Medical Physics; Biomedical engineering; Biomedical Engineering and Bioengineering; Biophysics; Biosensors; Bladder; Computers; Engineering; Engineering Fluid Dynamics; Female; Microelectromechanical systems; Monitoring systems; Monitoring, Physiologic - instrumentation; Monitoring, Physiologic - methods; Nanotechnology; Pressure; Prostheses and Implants; Swine; Transducers, Pressure; Transplants & implants; Urinary Bladder - physiopathology; Wireless; Patient monitoring; Telemedicine; Bladder; MEMS; Implantable; Telemetry; Pressure sensor
• ISSN: 1387-2176; 1572-8781
• DOI: 10.1007/s10544-008-9232-1

A fully implantable wireless pressure sensor system was developed to monitor bladder pressures in vivo . The system comprises a small commercial pressure die connected via catheter to amplifying electronics, a microcontroller, wireless transmitter, battery, and a personal digital assistant (PDA) or computer to receive the wireless data. The sensor is fully implantable and transmits pressure data once every second with a pressure detection range of 1.5 psi gauge and a resolution of 0.02 psi. In vitro calibration measurements of the device showed a high degree of linearity and excellent temporal response. The implanted device performed continuously in vivo in several porcine studies lasting over 3 days. This system can be adapted for other pressure readings, as well as other vital sign measurements; it represents the first step in developing a ubiquitous sensing platform for telemedicine and remote patient monitoring.