BNP: Is it an ideal marker to assess volume status in patients with hyponatremia and natriuresis?

A number of variables affect plasma brain natriuretic peptide and N-terminal pro brain natriuretic peptide levels, including the assay used, age (higher normal values are observed with increasing age), sex (higher values are observed in women), body mass index (lower levels are observed with a highe...

Full description

Saved in:
Bibliographic Details
Published inNeurology India Vol. 66; no. 5; pp. 1392 - 1393
Main Authors Azim, Afzal, Jena, Sunil
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer India Pvt. Ltd 01.09.2018
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Subjects
Amino acids
Body mass index
Diagnosis
Fluids
Heart cells
Heart failure
Humans
Hyponatremia
Mortality
Natriuresis
Natriuretic Peptide, Brain
Natriuretic peptides
Patient outcomes
Peptide Fragments
Peptides
Pilot Projects
Pulmonary arteries
Sepsis
Online AccessGet full text

Cover

More Information
Summary:A number of variables affect plasma brain natriuretic peptide and N-terminal pro brain natriuretic peptide levels, including the assay used, age (higher normal values are observed with increasing age), sex (higher values are observed in women), body mass index (lower levels are observed with a higher body mass index) renal dysfunction, inflammatory conditions, steroid therapy and diurnal variation. [...]for correction of hyponatremia, fluid restriction is needed in SIADH and fluid repletion is required in CSW. The presence of an “extreme” CVP value may be more helpful to guide in fluid administration than the presence of intermediate values. [...]the correlation of CVP <5cm of H2O combined with an elevated NT-ProBNP value to diagnose CSW may hold true but at present appears to be exploratory in status.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.241391