Aspiration–sclerotherapy Results in Effective Control of Liver Volume in Patients with Liver Cysts

• Published in: Digestive diseases and sciences Vol. 53; no. 8; pp. 2251 - 2257
• Main Authors: van Keimpema, Loes, de Koning, Daan B., Strijk, Simon P., Drenth, Joost P. H.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.08.2008; Springer; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Biochemistry; Biological and medical sciences; Cysts - complications; Cysts - pathology; Cysts - therapy; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Gastroenterology; Hepatology; Humans; Liver - pathology; Liver Diseases - complications; Liver Diseases - pathology; Liver Diseases - therapy; Male; Medicine; Medicine & Public Health; Middle Aged; Oncology; Organ Size; Original Paper; Sclerotherapy; Severity of Illness Index; Suction; Surveys and Questionnaires; Tomography, X-Ray Computed; Transplant Surgery; Treatment Outcome; Ultrasonography, Interventional; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Liver cyst; Ethanol; Aspiration; Volumetry; PCLD; Human; Liver; Liver cyst .PCLD; Gastroenterology; Cyst; Metabolic diseases; Benign neoplasm; Sclerotherapy
• ISSN: 0163-2116; 1573-2568
• DOI: 10.1007/s10620-007-0121-x

Purpose To study the extent to which aspiration–sclerotherapy reduces liver volume and whether this therapy results in relief of symptoms. Results Four patients, group I, with isolated large liver cysts, and 11 patients, group II, with polycystic livers, underwent aspiration–sclerotherapy. Average volume of aspirated cyst fluid was 1,044 ml (range 225–2,000 ml) in group I and 1,326 ml (range 40–4,200 ml) in group II. Mean liver volume before the procedure was 2,157 ml (range 1,706–2,841 ml) in group I and 4,086 ml (range 1,553–7,085 ml) in group II. This decreased after the procedure to 1,757 ml (range 1,479–2,187 ml) in group I. In group II there was a statistically significant decrease to 3,347 ml (range 1,249–6,930 ml, P  = 0.008). Volume reduction was 17.1% (range −34.7% to −4.1%) and 19.2% (range −53.9% to +2.4%) in groups I and II, respectively. Clinical severity of all symptoms decreased, except for involuntary weight loss and pain in group II. Conclusion Aspiration–sclerotherapy is an effective means of achieving liver volume reduction and relief of symptoms.