Interaction of Diphenyltin(IV) Dichloride with Some Selected Bioligands

The interaction of diphenyltin(IV) with selected bioligands having a variety of model functional groups were investigated using the potentiometric technique. The hydrolysis constants of diphenyltin(IV) cation and the step-wise formation constants of the complexes formed in solution were calculated u...

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Published inChemical & pharmaceutical bulletin Vol. 49; no. 3; pp. 253 - 257
Main Authors MOHAMED, Mahmoud Mohamed Ahmed, SHOUKRY, Mohamed Mohamed
Format Journal Article
LanguageEnglish
Published Tokyo The Pharmaceutical Society of Japan 01.03.2001
Maruzen
Japan Science and Technology Agency
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Abstract The interaction of diphenyltin(IV) with selected bioligands having a variety of model functional groups were investigated using the potentiometric technique. The hydrolysis constants of diphenyltin(IV) cation and the step-wise formation constants of the complexes formed in solution were calculated using the non linear least-squares program MINIQUAD-75. The participation of different ligand functional groups in binding to organotin is discussed. The concentration distribution of the various complex species was evaluated as a function of pH.
AbstractList The interaction of diphenyltin(IV) with selected bioligands having a variety of model functional groups were investigated using the potentiometric technique. The hydrolysis constants of diphenyltin(IV) cation and the step-wise formation constants of the complexes formed in solution were calculated using the non linear least-squares program MINIQUAD-75. The participation of different ligand functional groups in binding to organotin is discussed. The concentration distribution of the various complex species was evaluated as a function of pH.
Author MOHAMED, Mahmoud Mohamed Ahmed
SHOUKRY, Mohamed Mohamed
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Issue 3
Keywords Equilibrium constant
Thiol
Organic ligand
Stability constant
Penicillamine
Sulfur containing aminoacid
α-Aminoacid
Tin IV Complexes
Medium effect
pH
Chloro complex
Aminothiol
Tin Organic compounds
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SubjectTerms Algorithms
amino acid
Chemical Phenomena
Chemistry
Chemistry, Physical
dicarboxylic acid
diphenyltin(IV) dichloride
DNA constituent
Drug Carriers - chemistry
equilibrium study
Exact sciences and technology
Ge, sn, pb derivatives
Hydrogen-Ion Concentration
Indicators and Reagents
Ligands
Organic chemistry
Organometalloidal and organometallic compounds
Organotin Compounds - chemistry
peptide
Potentiometry
Preparations and properties
Title Interaction of Diphenyltin(IV) Dichloride with Some Selected Bioligands
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