The public health control of scabies: priorities for research and action
Scabies is a parasitic disease of the skin that disproportionately affects disadvantaged populations. The disease causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease. Scientific advances from the past 5 years suggest that scabies is amenable to populatio...
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Published in | The Lancet (British edition) Vol. 394; no. 10192; pp. 81 - 92 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
06.07.2019
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Scabies is a parasitic disease of the skin that disproportionately affects disadvantaged populations. The disease causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease. Scientific advances from the past 5 years suggest that scabies is amenable to population-level control, particularly through mass drug administration. In recognition of these issues, WHO added scabies to the list of neglected tropical diseases in 2017. To develop a global control programme, key operational research questions must now be addressed. Standardised approaches to diagnosis and methods for mapping are required to further understand the burden of disease. The safety of treatments for young children, including with ivermectin and moxidectin, should be investigated. Studies are needed to inform optimum implementation of mass treatment, including the threshold for intervention, target, dosing, and frequency. Frameworks for surveillance, monitoring, and evaluation of control strategies are also necessary. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 Contributors DaE and ACS conceived the project. DaE searched and reviewed the literature, wrote the first draft of the manuscript, made revisions, and prepared figure 3. DaE, LR, MJW, JMK, and ACS reviewed prevalence data for figure 2. DaE, PTC, MM, AWS, JMK, and ACS contributed to further development of the structure and content. All authors reviewed drafts of the manuscript, provided comments and critical review, helped to revise the manuscript, and agreed to the final version. |
ISSN: | 0140-6736 1474-547X 1474-547X |
DOI: | 10.1016/S0140-6736(19)31136-5 |