Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Ev...

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Bibliographic Details
Published inAntibiotics Vol. 4; no. 2; pp. 136 - 159
Main Authors Kumar, Vineeth T V, Holthausen, David, Jacob, Joshy, George, Sanil
Format Journal Article Book Review
LanguageEnglish
Published Switzerland MDPI AG 30.03.2015
MDPI
Subjects
Anti-microbial peptides
Asian frog
Host defense peptides
Multi-drug resistance
Review
Anti-microbial peptides
Multi-drug resistance
Asian frog
Host defense peptides
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Summary:Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Even though HDPs from 60 Asian frog species belonging to 15 genera have been characterized, research into these peptides is at a very early stage. The purpose of this review is to showcase the status of peptide research in Asia. Here we provide a summary of HDPs from Asian frogs.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics4020136