Three-dimensional visualization of the total mesorectal excision plane for dissection in rectal cancer surgery and its ability to predict surgical difficulty

• Published in: Scientific reports Vol. 13; no. 1; p. 2130
• Main Authors: Nagai, Yuzo, Kawai, Kazushige, Nozawa, Hiroaki, Sasaki, Kazuhito, Murono, Koji, Emoto, Shigenobu, Yokoyama, Yuichiro, Matsuzaki, Hiroyuki, Abe, Shinya, Sonoda, Hirofumi, Yoshioka, Yuichiro, Shinagawa, Takahide, Ishihara, Soichiro
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 06.02.2023; Nature Publishing Group UK; Nature Portfolio
• Subjects: Body mass index; Cancer; Cancer surgery; Colorectal cancer; Dissection; Humans; Imaging, Three-Dimensional; Laparoscopy - methods; Pelvis; Pelvis - pathology; Rectal Neoplasms - diagnostic imaging; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Rectum; Rectum - diagnostic imaging; Rectum - pathology; Rectum - surgery; Regression analysis; Retrospective Studies; Robotic surgery; Treatment Outcome
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-29426-x

Total mesorectal excision (TME) for rectal cancer is often technically challenging. We aimed to develop a method for three-dimensional (3D) visualization of the TME dissection plane and to evaluate its ability to predict surgical difficulty. Sixty-six patients with lower rectal cancer who underwent robot-assisted surgery were retrospectively analyzed. A 3D TME dissection plane image for each case was reconstructed using Ziostation2. Subsequently, a novel index that reflects accessibility to the deep pelvis during TME, namely, the TME difficulty index, was defined and measured. Representative bony pelvimetry parameters and clinicopathological factors were also analyzed. The operative time for TME was used as an indicator of surgical difficulty. Univariate regression analysis revealed that sex, body mass index, mesorectal fat area, and TME difficulty index were associated with the operative time for TME, whereas bony pelvimetry parameters were not. Multivariate regression analysis found that TME difficulty index (β = - 0.398, P = 0.0025) and mesorectal fat area (β = 0.223, P = 0.045) had significant predictability for the operative time for TME. Compared with conventional bony pelvimetry parameters, the TME difficulty index and mesorectal fat area might be more useful in predicting the difficulty of rectal cancer surgery.