Green Chemistry Metrics with Special Reference to Green Analytical Chemistry

• Published in: Molecules Vol. 20; no. 6; pp. 10928 - 10946
• Main Authors: Tobiszewski, Marek, Marć, Mariusz, Gałuszka, Agnieszka, Namieśnik, Jacek
• Format: Journal Article Book Review
• Language: English
• Published: Switzerland MDPI AG 12.06.2015; MDPI
• Subjects: Analytical chemistry; atom economy; E-Factor; EATOS; eco-footprint; Eco-Scale; Environment; environmental impact; green analytical chemistry metrics; Green chemistry; green chemistry metrics; Green Chemistry Technology - education; Green Chemistry Technology - methods; Review; eco-footprint; E-Factor; green analytical chemistry metrics; EATOS; environmental impact; atom economy; Eco-Scale; green chemistry metrics
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules200610928

The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-established and recently developed green analytical chemistry metrics, including NEMI labeling and analytical Eco-scale, are presented. Additionally, this paper focuses on the possibility of the use of multivariate statistics in evaluation of environmental impact of analytical procedures. All the above metrics are compared and discussed in terms of their advantages and disadvantages. The current needs and future perspectives in green chemistry metrics are also discussed.