The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces

Gram-positive soil bacteria included in the genus produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the strain has generated greater interest as a host bacterium for the overproduction of homologous and he...

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Bibliographic Details
Published inAntibiotics (Basel) Vol. 7; no. 2; p. 33
Main Authors Gullón, Sonia, Mellado, Rafael P
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 14.04.2018
MDPI
Subjects
Amino acids
Bacteria
Biosynthesis
E coli
Enzymes
Gene expression
Genomes
Gram-positive bacteria
Homology
Industrial applications
Mammals
Metabolites
Peptides
Proteins
Review
Secondary metabolites
Secretion
secretion pathways
secretory proteins
signal peptides
Soil bacteria
Soil microorganisms
Streptomyces
Streptomyces lividans
Stress response
Streptomyces lividans
signal peptides
secretion pathways
secretory proteins
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Summary:Gram-positive soil bacteria included in the genus produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the strain has generated greater interest as a host bacterium for the overproduction of homologous and heterologous hydrolytic enzymes as an industrial application, which has considerably increased scientific interest in the characterization of secretion routes in this bacterium. This review will focus on the secretion machinery in .
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics7020033