Carbohydrate Sensing Through the Transcription Factor ChREBP

• Published in: Frontiers in genetics Vol. 10; p. 472
• Main Authors: Ortega-Prieto, Paula, Postic, Catherine
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media 04.06.2019; Frontiers Media S.A
• Subjects: Biochemistry, Molecular Biology; carbohydrate sensing; ChREBP; Genetics; insulin sensitivity; Life Sciences; metabolism; Molecular biology; transcriptional regulation; insulin sensitivity; ChREBP; metabolism; carbohydrate sensing; transcriptional regulation

Carbohydrate response element binding protein (ChREBP) is a carbohydrate-signaling transcription factor that in the past years has emerged as a central metabolic regulator. ChREBP expression is mostly abundant in active sites of lipogenesis including liver and white and brown adipose tissues. ChREBP...