The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery

• Published in: Journal of orthopaedic surgery and research Vol. 15; no. 1; p. 117
• Main Authors: Ko, Sangbong, Chae, Seungbum, Choi, Wonkee, Kwon, Jaibum, Choi, Je-Yong
• Format: Journal Article
• Language: English
• Published: England BioMed Central 24.03.2020; BMC
• Subjects: 25-Hydroxyvitamin D; Age; Aged; Dietary Supplements; Female; Females; Functional Outcome; Humans; Lumbar spine; Lumbar Vertebrae - surgery; Male; Middle Aged; Orthopedics; Pain; Patients; Prevention; Quality of Life; Questionnaires; Recovery of Function - physiology; Spinal Fusion - trends; Spinal Stenosis; Spinal Stenosis - blood; Spinal Stenosis - diet therapy; Spinal Stenosis - surgery; Statistical analysis; Supplements; Surgery; Treatment Outcome; Vitamin D; Vitamin D - administration & dosage; Vitamin D - analogs & derivatives; Vitamin D Deficiency - blood; Vitamin D Deficiency - diet therapy; Vitamin D Deficiency - surgery; Vitamin deficiency; United States > US; Quality of Life; Lumbar spine; Spinal Stenosis; Vitamin D; Functional Outcome; Surgery
• ISSN: 1749-799X; 1749-799X
• DOI: 10.1186/s13018-020-01629-2

This is a retrospective cohort comparative study. Vitamin D supplementation is considered to be associated with good functional outcome. Thus, a few studies have proposed vitamin D supplementation is benefit to the functional outcome in LSS requiring surgery. The purpose of this study is to identify the prevalence of vitamin D deficiency in patients with LSS requiring surgery, and to compare the differences between the cases whether vitamin D is supplemented and vitamin D is not supplemented in terms of a QoL during postoperative 2 year. All patients with LSS who underwent surgery from March 1, 2015 to August 31, 2016 were enrolled. Among them, 61 patients with vitamin D deficiency were divided into two groups (supplemented group (A) and non-supplemented group (B)). Functional outcomes using Oswestry Disability Index (ODI) and Rolland Morris Disability Index (RMDQ) and QoL using SF-36 were evaluated at 12-month and 24-month follow-up periods. Differences in functional score and SF-36 between the vitamin D supplemented and non-supplemented group were compared. Among the total 102 patients, 78 patients (76.5%) had vitamin D deficiency. Of the 78 patients, 61 patients were included, 27 patients were group A and 27 patients were group B. There was no difference in age and 25-OHD level between the two groups (all 0 > 0.05). Group A were better functional outcomes at 2 years after surgery (p < 0.05). On the QoL, group A were higher score than group B from 12 month later after surgery (p < 0.05). Vitamin D deficiency was highly prevalent in LSS patients (76.5%). Assessment of serum 25-hydroxyvitamin D (25(OH)D) is recommended in LSS needing surgical intervention and active treatment vitamin D supplementation and maintenance of normal range should be considered for better postoperative functional outcome and QoL.