Phlegmasia cerulea dolens associated with acute coronavirus disease 2019 pneumonia despite supratherapeutic warfarin anticoagulation

Patients with acute coronavirus disease 2019 (COVID-19) respiratory infection are associated with concomitant thromboembolic complications and a hypercoagulable state. Although these mechanisms are not completely understood, unique alterations in the serum markers for hemostasis and thrombosis have...

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Bibliographic Details
Published inJournal of vascular surgery cases and innovative techniques Vol. 6; no. 4; pp. 653 - 656
Main Authors Chun, Tristen T., Jimenez, Juan Carlos, Pantoja, Joe L., Moriarty, John M., Freeman, Shanna
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.12.2020
Elsevier
Subjects
Case report
Coronavirus disease 2019
Deep vein thrombosis
Gangrene
Phlegmasia cerulea dolens
Thrombectomy
Deep vein thrombosis
Gangrene
Thrombectomy
Coronavirus disease 2019
Phlegmasia cerulea dolens
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Summary:Patients with acute coronavirus disease 2019 (COVID-19) respiratory infection are associated with concomitant thromboembolic complications and a hypercoagulable state. Although these mechanisms are not completely understood, unique alterations in the serum markers for hemostasis and thrombosis have been detected. A high index of suspicion is required by vascular surgeons for patients presenting with this novel virus. We present the case of a 51-year-old man with acute COVID-19 pneumonia who developed phlegmasia cerulea dolens despite chronic warfarin therapy and a supratherapeutic international normalized ratio.
ISSN:2468-4287
2468-4287
DOI:10.1016/j.jvscit.2020.10.002