Correlation of clinical staging and MRI staging for cervical cancer

• Published in: Egyptian Journal of Radiology and Nuclear Medicine Vol. 52; no. 1; pp. 162 - 7
• Main Authors: Nawapun, Supajit, Aphinives, Chalida, Srisitthiprapha, Wiranya, Thamronganantasakul, Komsan, Temtanakitpaisan, Amornrat
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 06.07.2021; Springer; Springer Nature B.V; SpringerOpen
• Subjects: Abdomen; Agreements; Biopsy; Bladder; CA cervix; Cancer therapies; Care and treatment; Cervical cancer; Chemotherapy; Clinical medicine; Clinical practice guidelines; Clinical staging; Gynecology; Health aspects; Histology; Hydronephrosis; Imaging; Kappa coefficient; Kidneys; Magnetic resonance imaging; Medicine; Medicine & Public Health; Metastasis; MRI staging; Nuclear Medicine; Patients; Radiation; Radiography; Radiology; Ultrasonic imaging; Vagina; Women; Thailand; Clinical staging; MRI staging; CA cervix; Cervical cancer
• ISSN: 0378-603X; 2090-4762
• DOI: 10.1186/s43055-021-00544-8

Background Cervical cancer is a major public health problem for women. Accurate staging may lead to proper management of cervical cancer. We retrospectively reviewed all patients with cervical cancer who underwent pre-treatment MRI between January 2009 and December 2018 and analyzed the correlation between the clinical staging and MRI staging. Results Correlation of overall clinical and MRI staging by percent agreement is moderate (73.9%), but the kappa coefficient showed a slight correlation. The correlation of clinical and MRI findings in the vaginal invasion, pelvic sidewall invasion, adjacent pelvic organ invasion, and spreading to distant organ also showed moderate-to-strong correlation by percent agreement (ranging from 67.6 to 91.9%) but slight correlation between clinical and MRI examinations by kappa or weighted kappa coefficient (K = 0.000–0.128 w ). Conclusion In patients with cervical cancer, pretreatment MRI provides higher spatial soft tissue resolution which can define pelvic tumor extent, including a more accurate assessment of tumor size (due to multiplanar evaluation), parametrial invasion, pelvic sidewall invasion, and adjacent pelvic organ invasion. This could potentially lead to a reduction in staging morbidity by invasive investigation such as cystoscopy and proctoscopy.