Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

• Published in: Infection & chemotherapy Vol. 51; no. 2; pp. 177 - 182
• Main Authors: Ahn, Kwangjin, Hwang, Gyu Yel, Kim, Young Keun, Kim, Hyo Youl, Jeong, Hye Ran, Hong, Jun Sung, Uh, Young
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 01.06.2019; 대한감염학회
• Subjects: Brief Communication; 내과학; Outbreak control; Oxacillin-hydrolyzing beta-lactamase; New Delhi metallo-enzyme carbapenemase; Carbapenemase-producing Enterobacteriaceae; Escherichia coli
• ISSN: 2093-2340; 2092-6448
• DOI: 10.3947/ic.2019.51.2.177

Carbapenemase-producing (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant strains. All of isolates co-produced and carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.