Solution structure of μ-conotoxin GIIIA analysed by 2D-NMR and distance geometry calculations
We have investigated the structure of μ-conotoxin GIIIA by 2D-NMR methods. The assignment of 1H NMR spectra and a quantitative analysis of NOE and J-coupling data are presented. These results were used for the calculation of secondary structure elements of μ-conotoxin GIIIA. Distance geometry calcul...
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Published in | FEBS letters Vol. 278; no. 2; pp. 160 - 166 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Amsterdam
Elsevier B.V
28.01.1991
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | We have investigated the structure of μ-conotoxin GIIIA by 2D-NMR methods. The assignment of
1H NMR spectra and a quantitative analysis of NOE and J-coupling data are presented. These results were used for the calculation of secondary structure elements of μ-conotoxin GIIIA. Distance geometry calculations were carried out to define the global folding of the peptide. |
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ISSN: | 0014-5793 1873-3468 |
DOI: | 10.1016/0014-5793(91)80107-E |