Current therapeutic options for Huntington's disease: Good clinical practice versus evidence-based approaches?

• Published in: Movement disorders Vol. 29; no. 11; pp. 1404 - 1413
• Main Authors: Killoran, Annie, Biglan, Kevin M.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 15.09.2014; Wiley Subscription Services, Inc
• Subjects: Cognition Disorders - etiology; Cognition Disorders - therapy; Evidence-Based Medicine; expert opinion; Humans; Huntington Disease - complications; Huntington Disease - therapy; Huntington's disease; Mental Disorders - etiology; Mental Disorders - therapy; Movement disorders; Movement Disorders - etiology; Movement Disorders - therapy; treatment; treatment; expert opinion; Huntington's disease; evidence-based medicine

ABSTRACT Therapeutic decision‐making in Huntington's disease (HD) is often guided by clinical experience, because of the limited empirical evidence available. The only medication for HD that has met the regulatory hurdle for approval is tetrabenazine, indicated for the treatment of chorea. Howe...