Prevalence and determinants of diabetes mellitus and glucose intolerance in a Canarian Caucasian population - comparison of the 1997 ADA and the 1985 WHO criteria. The Guía Study

• Published in: Diabetic medicine Vol. 18; no. 3; pp. 235 - 241
• Main Authors: De Pablos-Velasco, P. L., Martínez-Martín, F. J., Rodríguez-Pérez, F., Anía, B. J., Losada, A., Betancor, P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.03.2001; Blackwell
• Subjects: Adult; Age Distribution; Aged; Aged, 80 and over; Associated diseases and complications; Atlantic Islands - epidemiology; Biological and medical sciences; Body Constitution; Body Mass Index; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - prevention & control; Diabetes Mellitus - epidemiology; Diabetes. Impaired glucose tolerance; dislipidaemia; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; epidemiology; European Continental Ancestry Group; Fasting; Female; Glucose Intolerance - epidemiology; Glucose Tolerance Test; Humans; hypertension; impaired fasting glucose; impaired glucose tolerance; Lipids - blood; Male; Medical sciences; Middle Aged; obesity; Prevalence; Sex Factors; Spain - epidemiology; United States; Voluntary Health Agencies; World Health Organization; Atlantic Ocean Islands; Canary Islands; United States; Atlantic Islands; Spain; Endocrinopathy; Vascular disease; Human; Hyperglycemia; Prevalence; Microangiopathy; Diabetes mellitus; Cardiovascular disease; Complication; Impaired glucose tolerance; Epidemiology
• ISSN: 0742-3071; 1464-5491
• DOI: 10.1046/j.1464-5491.2001.00451.x

Summary Aims  To estimate the prevalence of diabetes mellitus, impaired fasting glucose and impaired glucose tolerance in a Canarian population according to the 1997 ADA and the 1985 WHO criteria; and to study the cardiovascular risk factors associated with these categories. Methods  A total of 691 subjects over 30 years old were chosen in a random sampling of the population (stratified by age and sex). An oral glucose tolerance test was performed (excluding known diabetic patients) and lipids were determined in the fasting state. Anthropometric and blood pressure measurements were performed, and history of smoking habits and medications was recorded. Results  The prevalence of diabetes was 15.9% (1997 ADA) and 18.7% (1985 WHO); the prevalence of impaired fasting glucose and impaired glucose tolerance was 8.8 and 17.1%, respectively. The age‐adjusted prevalence of diabetes (Segi's standard world population) for the population aged 30–64 years was 12.4% (1985 WHO). The risk factors significantly associated with diabetes (1997 ADA and 1985 WHO) were age, body mass index; waist‐to‐hip ratio, systolic and mean blood pressure, triglycerides, total cholesterol and low HDL‐cholesterol. Age, body mass index and systolic blood pressure were associated with impaired fasting glucose and impaired glucose tolerance; triglycerides were also associated with impaired fasting glucose. Conclusions  The prevalence of diabetes mellitus and glucose intolerance in Guía is one of the highest among studied Caucasian populations. The new 1997 ADA criteria estimate a lower prevalence of diabetes. Impaired fasting glucose also had a lower prevalence than impaired glucose intolerance and the overlap of these categories was modest.