Use of radiation and a slow-release cisplatin formulation for treatment of canine nasal tumors
The purpose of this study was to evaluate the combined use of radiation and a slow‐release cisplatin chemotherapy formulation for treatment of malignant nasal tumors in dogs. In this retrospective analysis, 51 dogs were evaluated with respect to treatment toxicity, tumor type, stage of disease, crib...
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Published in | Veterinary radiology & ultrasound Vol. 45; no. 6; pp. 577 - 581 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Science Inc
01.11.2004
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Subjects | |
Online Access | Get full text |
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Summary: | The purpose of this study was to evaluate the combined use of radiation and a slow‐release cisplatin chemotherapy formulation for treatment of malignant nasal tumors in dogs. In this retrospective analysis, 51 dogs were evaluated with respect to treatment toxicity, tumor type, stage of disease, cribriform plate involvement, and overall survival. In general, treatment was well tolerated. Mean and median survival as assessed by the Kaplan–Meier product limit method was 570 and 474 days, respectively. No other factors, including tumor type, stage of disease, or cribriform plate invasion had a significant impact on survival. In conclusion, a combination of slow release cisplatin chemotherapy and radiation for the treatment of canine nasal tumors is well tolerated. Results of this analysis warrant further study to elucidate possible other beneficial radiation potentiating drugs and dosing schedules. |
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Bibliography: | ArticleID:VRU04100 istex:1C78A5445E93E7CB98172B88274DDF9F0230008C ark:/67375/WNG-KT477XQ0-B |
ISSN: | 1058-8183 1740-8261 |
DOI: | 10.1111/j.1740-8261.2004.04100.x |