Antioxidants: Friend or foe?

Reactive oxygen species are the intermediates that are formed during the normal meta-bolic process which are effectively neutralized by the antioxidant system of the body. Any imbalance in this neutralization process causes oxidative stress which has been implicated as one of the cause in diseases s...

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Published inAsian Pacific journal of tropical medicine Vol. 10; no. 12; pp. 1111 - 1116
Main Authors Sarangarajan, R., Meera, S., Rukkumani, R., Sankar, P., Anuradha, G.
Format Journal Article
LanguageEnglish
Published India Elsevier B.V 01.12.2017
Department of Oral Pathology,Madha Dental College,Kundrathur,Chennai,India%Private Dental Practitioner,Sree Sai Dental Care,Chennai,India%Department of Biochemistry and Molecular Biology,School of Life Sciences,Pondicherry University,Puducherry,India%Private Dental Practitioner,Sai Raghav Dental Clinic,Chennai,India
Subjects
Antioxidants
Oxidative stress
Reactive oxygen species
Therapeutic agent
Antioxidants
Oxidative stress
Reactive oxygen species
Therapeutic agent
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Summary:Reactive oxygen species are the intermediates that are formed during the normal meta-bolic process which are effectively neutralized by the antioxidant system of the body. Any imbalance in this neutralization process causes oxidative stress which has been implicated as one of the cause in diseases such as Alzheimer's disease,cardiovascular disorders,cancer etc. Research has enabled the use of antioxidants as therapeutic agents in the treatment of various diseases. Literature also puts forth the negative effects of using antioxidants in the treatment of diseases. This review is a compilation of both the beneficial and detrimental effects of use of antioxidants in the treatment of diseases such as cancer,cardiovascular diseases,diabetes and oral diseases.
Bibliography:Reactive oxygen species are the intermediates that are formed during the normal meta-bolic process which are effectively neutralized by the antioxidant system of the body. Any imbalance in this neutralization process causes oxidative stress which has been implicated as one of the cause in diseases such as Alzheimer's disease,cardiovascular disorders,cancer etc. Research has enabled the use of antioxidants as therapeutic agents in the treatment of various diseases. Literature also puts forth the negative effects of using antioxidants in the treatment of diseases. This review is a compilation of both the beneficial and detrimental effects of use of antioxidants in the treatment of diseases such as cancer,cardiovascular diseases,diabetes and oral diseases.
R.Sarangarajan[1];S.Meera[2];R.Rukkumani[3];P.Sankar[3];G.Anuradha[4]
Antioxidants;Oxidative stress;Reactive oxygen species;Therapeutic agent
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1995-7645
2352-4146
DOI:10.1016/j.apjtm.2017.10.017