Insurance status predicts self-reported influenza vaccine coverage among pregnant women in the United States: A cross-sectional analysis of the National Health Interview Study Data from 2012 to 2018

• Published in: Vaccine Vol. 39; no. 15; pp. 2068 - 2073
• Main Authors: Cambou, Mary Catherine, Copeland, Timothy P., Nielsen-Saines, Karin, Macinko, James
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 08.04.2021; Elsevier Limited
• Subjects: Confidence intervals; Cross-Sectional Studies; Demographics; Demography; Determinants; Female; Graduate schools; Graduate studies; Health insurance; Humans; Immunization; Influenza; Influenza vaccine; Influenza vaccine coverage; Influenza Vaccines; Influenza, Human - prevention & control; Insurance; Insurance Coverage; Maternal vaccination; Polls & surveys; Population Surveillance; Poverty; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Racial identity; Racism; Regression analysis; Self Report; Statistical analysis; United States; Vaccination; Vaccines; Womens health; United States; United States > US; Determinants; Influenza vaccine coverage; Pregnant women; Influenza vaccine; Maternal vaccination
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2021.03.026

While the influenza vaccine is recommended for all pregnant women, influenza vaccine coverage among this high-risk population remains inadequate. Factors associated with vaccine coverage among pregnant women, including insurance status, are poorly understood. In a cross-sectional study of the National Health Interview Survey (NHIS) data from 2012 to 2018, we evaluated predictors of self-reported influenza vaccine coverage in pregnant women. Among 1,942 pregnant women surveyed, 39% reported receiving the influenza vaccine in accordance with national recommendations. Influenza vaccine coverage increased by 8 percentage points from 2012 to 2018. Only 15% of uninsured pregnant women received the influenza vaccine, compared to 41% of those with insurance (design-corrected F-test, p-value < 0.001). In the multivariate Poisson regression analysis, significant predictors of influenza vaccine coverage were health insurance (prevalence ratio [PR] 1.90, 95% confidence interval [CI] 1.23–2.93), ratio of household income to federal poverty level (FPL) threshold greater than 400% (PR 1.54, 95% CI 1.20–1.96), graduate school education (PR 1.52, 95% CI 1.04–2.23), and the 2015–2018 survey year period (PR 1.27, 95% CI 1.08–1.49). While previous literature focuses heavily on demographics, our research underscores the need to further explore modifiable factors that impact vaccine uptake during pregnancy, particularly the interplay between health insurance and access to care.