Lack of association between the G+2044A polymorphism of interleukin-13 gene and chronic obstructive pulmonary disease: a meta-analysis

• Published in: Molecular biology reports Vol. 41; no. 9; pp. 6297 - 6303
• Main Authors: Duan, Lian, Liang, Rui, Wang, Zhendong, Lei, Lei, Jin, Lianhong, Shen, Jingling, Jin, Shoude
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer-Verlag 01.09.2014; Springer Netherlands; Springer Nature B.V
• Subjects: Alleles; Animal Anatomy; Animal Biochemistry; Biomedical and Life Sciences; Chronic obstructive pulmonary disease; experimental design; Genes; Genetic Association Studies; Genetic Predisposition to Disease; genotype; genotyping; Histology; Humans; interleukin-13; Interleukin-13 - genetics; Life Sciences; Meta-analysis; Morphology; patients; Polymorphism; Polymorphism, Single Nucleotide; Pulmonary Disease, Chronic Obstructive - genetics; Risk Factors; Th2 Cells; 13; Chronic obstructive pulmonary disease; Association; G+2044A; Polymorphism

Numerous studies have investigated association of interleukin-13 (IL-13) G+2044A polymorphism with COPD susceptibility; however, the results were inconsistent and inconclusive. To evaluate the association between the IL-13 G+2044A polymorphism and susceptibility to COPD, a meta-analysis of published...