Phosphatidylinositol Synthase and Diacylglycerol Platforms Bust a Move

Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These finding...

Full description

Saved in:
Bibliographic Details
Published inDevelopmental cell Vol. 21; no. 5; pp. 810 - 812
Main Authors Bankaitis, Vytas A., Grabon, Aby
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 15.11.2011
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell.
AbstractList Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell.
Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell.
Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell.Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell.
Author Bankaitis, Vytas A.
Grabon, Aby
Author_xml – sequence: 1
  givenname: Vytas A.
  surname: Bankaitis
  fullname: Bankaitis, Vytas A.
  email: vytas@med.unc.edu
  organization: Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7090, USA
– sequence: 2
  givenname: Aby
  surname: Grabon
  fullname: Grabon, Aby
  organization: Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7090, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/22075144$$D View this record in MEDLINE/PubMed
BookMark eNqFkUtvEzEUhS3Uij7gHyA0O7qZ1M-MhwUSFEortaISsLY8njuNI8dObSfS_Pt6lBQBi3Zl69zvHl2dc4IOfPCA0DuCZwST-fly1sPWgJtRTEiRZkV8hY6JbGRNhCAH5S8Yr4XEzRE6SWmJC0Ekfo2OKMWNIJwfo8u7RUjrhc62H531IdkcXPVz9HmhE1Ta99VXq83o7t1oIJbZndN5CHGVqi-blCtd3YYtvEGHg3YJ3u7fU_T78tuvi6v65sf364vPN7Xhrci1lLSlLQwSOtoKo2Eo75wL3BvKcEe7BvoBDyCIoAZa01DcckNa0eluELJjp-jTzne96VbQG_A5aqfW0a50HFXQVv078Xah7sNWMcrpnMli8GFvEMPDBlJWK5tKik57CJukWswxYYxO5NmzJGkYE7zgvKDv_77qzzlPMRfg4w4wMaQUYVDG5pJ5mI60ThGspk7VUu06VVOnk1rEssz_W37yf2FtHxWUPrYWokrGgjfQ2wgmqz7Y5w0eAdWvvn4
CitedBy_id crossref_primary_10_3390_ijms22147353
crossref_primary_10_1016_j_bbalip_2012_04_004
crossref_primary_10_1042_BST20140187
crossref_primary_10_7717_peerj_13417
crossref_primary_10_3390_ijms241612665
Cites_doi 10.1016/S0005-2760(97)00105-7
10.1016/j.devcel.2011.09.005
10.1016/j.tibs.2009.10.008
10.1016/j.bbalip.2007.03.009
10.1242/jcs.069773
10.1016/0304-4157(75)90017-9
10.1016/j.plipres.2009.06.001
10.1038/325726a0
10.1128/jb.172.7.4115-4117.1990
10.1016/S0021-9258(18)69403-7
ContentType Journal Article
Copyright 2011 Elsevier Inc.
Copyright © 2011 Elsevier Inc. All rights reserved.
2011 Elsevier Inc. All rights reserved. 2011
Copyright_xml – notice: 2011 Elsevier Inc.
– notice: Copyright © 2011 Elsevier Inc. All rights reserved.
– notice: 2011 Elsevier Inc. All rights reserved. 2011
DBID 6I.
AAFTH
AAYXX
CITATION
NPM
7S9
L.6
7X8
5PM
DOI 10.1016/j.devcel.2011.10.016
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
PubMed
AGRICOLA
AGRICOLA - Academic
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
PubMed
AGRICOLA
AGRICOLA - Academic
MEDLINE - Academic
DatabaseTitleList AGRICOLA

MEDLINE - Academic
PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1878-1551
EndPage 812
ExternalDocumentID PMC3242638
22075144
10_1016_j_devcel_2011_10_016
S1534580711004680
Genre Comment
Journal Article
GrantInformation_xml – fundername: NINDS NIH HHS
  grantid: R56 NS037723
– fundername: NIGMS NIH HHS
  grantid: R01 GM044530
– fundername: NINDS NIH HHS
  grantid: R01 NS037723
– fundername: National Institute of General Medical Sciences : NIGMS
  grantid: R01 GM044530-20 || GM
– fundername: National Institute of Neurological Disorders and Stroke : NINDS
  grantid: R56 NS037723-11A1 || NS
GroupedDBID ---
--K
0R~
1~5
2WC
4.4
457
4G.
5GY
62-
6I.
7-5
AACTN
AAEDT
AAEDW
AAFTH
AAIAV
AAIKJ
AAKRW
AALRI
AAUCE
AAVLU
AAXJY
AAXUO
ABJNI
ABMAC
ABMWF
ABVKL
ACGFO
ACGFS
ACNCT
ADBBV
ADEZE
ADJPV
AEFWE
AENEX
AEXQZ
AFFNX
AFTJW
AGHFR
AGKMS
AITUG
ALKID
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
ASPBG
AVWKF
AZFZN
BAWUL
CS3
D0L
DIK
DU5
E3Z
EBS
EJD
F5P
FCP
FDB
FEDTE
FIRID
HVGLF
HZ~
IHE
IXB
J1W
JIG
M3Z
M41
NCXOZ
O-L
O9-
OK1
P2P
RCE
RIG
ROL
RPZ
SDG
SES
SSZ
TR2
WQ6
ZA5
29F
53G
5VS
AAMRU
AAQFI
AAQXK
AAYWO
AAYXX
ABDGV
ABWVN
ACRPL
ACVFH
ADCNI
ADMUD
ADNMO
ADVLN
AETEA
AEUPX
AFPUW
AGCQF
AGQPQ
AIGII
AKAPO
AKBMS
AKRWK
AKYEP
APXCP
CITATION
FGOYB
OZT
R2-
UHS
EFKBS
NPM
7S9
L.6
7X8
5PM
ID FETCH-LOGICAL-c495t-882929ef8eb295caefb296450dc230b2b7edf0fe5152ce9c72094c195babf58b3
IEDL.DBID IXB
ISSN 1534-5807
1878-1551
IngestDate Thu Aug 21 18:29:59 EDT 2025
Thu Jul 10 17:32:53 EDT 2025
Sun Jul 27 06:28:16 EDT 2025
Mon Jul 21 06:07:24 EDT 2025
Tue Jul 01 02:37:32 EDT 2025
Thu Apr 24 23:01:46 EDT 2025
Fri Feb 23 02:26:41 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Language English
License http://www.elsevier.com/open-access/userlicense/1.0
https://www.elsevier.com/tdm/userlicense/1.0
Copyright © 2011 Elsevier Inc. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c495t-882929ef8eb295caefb296450dc230b2b7edf0fe5152ce9c72094c195babf58b3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-3
ObjectType-Commentary-1
OpenAccessLink https://www.sciencedirect.com/science/article/pii/S1534580711004680
PMID 22075144
PQID 1733540404
PQPubID 24069
PageCount 3
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_3242638
proquest_miscellaneous_904013328
proquest_miscellaneous_1733540404
pubmed_primary_22075144
crossref_citationtrail_10_1016_j_devcel_2011_10_016
crossref_primary_10_1016_j_devcel_2011_10_016
elsevier_sciencedirect_doi_10_1016_j_devcel_2011_10_016
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2011-11-15
PublicationDateYYYYMMDD 2011-11-15
PublicationDate_xml – month: 11
  year: 2011
  text: 2011-11-15
  day: 15
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Developmental cell
PublicationTitleAlternate Dev Cell
PublicationYear 2011
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Cockcroft, Carvou (bib3) 2007; 1771
Jensen, Schekman (bib5) 2011; 124
Imai, Gershengorn (bib4) 1987; 325
Kim, Guzman-Hernandez, Balla (bib6) 2011; 20
Bankaitis, Mousley, Schaaf (bib2) 2010; 35
Antonsson (bib1) 1997; 1348
Sasaki, Takasuga, Sasaki, Kofuji, Eguchi, Yamazaki, Suzuki (bib10) 2009; 48
Kinney, Carman (bib7) 1990; 172
Michell (bib8) 1975; 415
Paulus, Kennedy (bib9) 1960; 235
Cockcroft (10.1016/j.devcel.2011.10.016_bib3) 2007; 1771
Antonsson (10.1016/j.devcel.2011.10.016_bib1) 1997; 1348
Kim (10.1016/j.devcel.2011.10.016_bib6) 2011; 20
Imai (10.1016/j.devcel.2011.10.016_bib4) 1987; 325
Paulus (10.1016/j.devcel.2011.10.016_bib9) 1960; 235
Jensen (10.1016/j.devcel.2011.10.016_bib5) 2011; 124
Bankaitis (10.1016/j.devcel.2011.10.016_bib2) 2010; 35
Sasaki (10.1016/j.devcel.2011.10.016_bib10) 2009; 48
Kinney (10.1016/j.devcel.2011.10.016_bib7) 1990; 172
Michell (10.1016/j.devcel.2011.10.016_bib8) 1975; 415
22075145 - Dev Cell. 2011 Nov 15;21(5):813-24. doi: 10.1016/j.devcel.2011.09.005.
References_xml – volume: 124
  start-page: 1
  year: 2011
  end-page: 4
  ident: bib5
  publication-title: J. Cell Sci.
– volume: 35
  start-page: 150
  year: 2010
  end-page: 160
  ident: bib2
  publication-title: Trends Biochem. Sci.
– volume: 325
  start-page: 726
  year: 1987
  end-page: 728
  ident: bib4
  publication-title: Nature
– volume: 235
  start-page: 1303
  year: 1960
  end-page: 1311
  ident: bib9
  publication-title: J. Biol. Chem.
– volume: 172
  start-page: 4115
  year: 1990
  end-page: 4117
  ident: bib7
  publication-title: J. Bacteriol.
– volume: 1771
  start-page: 677
  year: 2007
  end-page: 691
  ident: bib3
  publication-title: Biochim. Biophys. Acta
– volume: 1348
  start-page: 179
  year: 1997
  end-page: 186
  ident: bib1
  publication-title: Biochim. Biophys. Acta
– volume: 48
  start-page: 307
  year: 2009
  end-page: 343
  ident: bib10
  publication-title: Prog. Lipid Res.
– volume: 20
  start-page: 813
  year: 2011
  end-page: 824
  ident: bib6
  publication-title: Dev. Cell
– volume: 415
  year: 1975
  ident: bib8
  publication-title: Biochim. Biophys. Acta
– volume: 1348
  start-page: 179
  year: 1997
  ident: 10.1016/j.devcel.2011.10.016_bib1
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/S0005-2760(97)00105-7
– volume: 20
  start-page: 813
  year: 2011
  ident: 10.1016/j.devcel.2011.10.016_bib6
  publication-title: Dev. Cell
  doi: 10.1016/j.devcel.2011.09.005
– volume: 35
  start-page: 150
  year: 2010
  ident: 10.1016/j.devcel.2011.10.016_bib2
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/j.tibs.2009.10.008
– volume: 1771
  start-page: 677
  year: 2007
  ident: 10.1016/j.devcel.2011.10.016_bib3
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbalip.2007.03.009
– volume: 124
  start-page: 1
  year: 2011
  ident: 10.1016/j.devcel.2011.10.016_bib5
  publication-title: J. Cell Sci.
  doi: 10.1242/jcs.069773
– volume: 415
  year: 1975
  ident: 10.1016/j.devcel.2011.10.016_bib8
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/0304-4157(75)90017-9
– volume: 48
  start-page: 307
  year: 2009
  ident: 10.1016/j.devcel.2011.10.016_bib10
  publication-title: Prog. Lipid Res.
  doi: 10.1016/j.plipres.2009.06.001
– volume: 325
  start-page: 726
  year: 1987
  ident: 10.1016/j.devcel.2011.10.016_bib4
  publication-title: Nature
  doi: 10.1038/325726a0
– volume: 172
  start-page: 4115
  year: 1990
  ident: 10.1016/j.devcel.2011.10.016_bib7
  publication-title: J. Bacteriol.
  doi: 10.1128/jb.172.7.4115-4117.1990
– volume: 235
  start-page: 1303
  year: 1960
  ident: 10.1016/j.devcel.2011.10.016_bib9
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)69403-7
– reference: 22075145 - Dev Cell. 2011 Nov 15;21(5):813-24. doi: 10.1016/j.devcel.2011.09.005.
SSID ssj0016180
Score 2.0533578
Snippet Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane...
Kim et al. (2011) challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane...
SourceID pubmedcentral
proquest
pubmed
crossref
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 810
SubjectTerms cell communication
endoplasmic reticulum
enzymes
myo-inositol
plasma membrane
synthesis
Title Phosphatidylinositol Synthase and Diacylglycerol Platforms Bust a Move
URI https://dx.doi.org/10.1016/j.devcel.2011.10.016
https://www.ncbi.nlm.nih.gov/pubmed/22075144
https://www.proquest.com/docview/1733540404
https://www.proquest.com/docview/904013328
https://pubmed.ncbi.nlm.nih.gov/PMC3242638
Volume 21
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Za9tAEF5CoJCX0uZonSZhA3kV1rXe1WPj1ISASyAJ-E3sMapdhGRsOaB_3xkdpk5SAkV62p2F1ewx32hnv2HsSjqQhiiGwBfWi50ZeQlOLE8Kg9ZSBuBLuig8_Tm6fYrvZmK2x8b9XRgKq-z2_nZPb3brrmTYaXO4XCyGD7hWY6HQRBLp2UiR3x7FqrnEN7veniSMgiZ7Ggl7JN1fn2tivBw8W8hbIk-K8aKs52-bp9fw82UU5V9mafKJfezwJP_edvkz24PikH1oM0zWR2xyPy_Xyzmq39UIKClCq8z5Q11UczRfXBeO3yy0rfNfeW1hhXX3ua4IyK759WZdcc2n5TMcs6fJj8fxrdelTvAsejyVh7gZcQ9kCh3nRFgNmaHzVeE7iz6HCY0El_kZIJoJLSRWhujm2SARRptMKBOdsP2iLOAr4zbLQiJ9i5IAYgiUQgyU4NK3ync60W7Aol5jqe14xSm9RZ72AWS_01bPKemZSrFwwLxtq2XLq_GOvOwHI92ZHylu_e-0vOzHLsWlQ-chuoBys04DGdFfL3wGjP9Dhr4U3fhQDdiXdri33Q1DhFvoj2LXdibCVoCYu3drisW8YfCOGp58dfrfH_WNHTQ_t-kVZ2y_Wm3gHNFRZS6a6f8HJlcOng
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VIkQviHdTCiwSHK34EWftA4eWEiW0qSq1lXIz3t0xSWXZUe0U-XfxB5nxIyI8VAmpik_rdbSe2Z35xjv7DcB7aVAqphhC29fWwKihFdLEsqSvyFtKB23JB4Wnp8Px5eDLzJ9twY_uLAynVba2v7HptbVuW_qtNPvLxaJ_Tmt14AfkIpn0bBjYbWblMVbfKW4rPk6OSMkfXHf0-eLT2GpLC1iaIoLSIlxJuACTgALL0NcxJor3H33baMLkylUSTWInSN7e1Rhq6VIYpJ3QV7FK_EB59L_34D6hD8nWYDI7XG9dDJ26XBuPzuLhdef16qQygzca04Y5lJPKuMz63_3hn3j397TNX_zg6DE8agGsOGhk9AS2MHsKD5qSltUzGJ3N82I5J32bihAsp4TlqTivsnJO_lLEmRFHi1hX6be00nhN987SuGTkXIjDVVGKWEzzG3wOl3ci0BewneUZ7oLQSeIyy5wXOjhAJwgIdIVka3RgmziMTQ-8TmKRbonMuZ5GGnUZa1dRI-eI5cyt1NgDa_3UsiHyuKW_7JQRbUzIiHzNLU--63QX0VrlDZg4w3xVRI70-DMb_Xog_tGH39TxPDfowctG3evhui7hOwqAaWgbE2HdganCN-9ki3lNGe7VxPzB3n-_1Ft4OL6YnkQnk9PjV7BTf1nny9-H7fJ6ha8JmpXqTb0UBHy967X3E3BlTNo
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Phosphatidylinositol+Synthase+and+Diacylglycerol+Platforms+Bust+a+Move&rft.jtitle=Developmental+cell&rft.au=Bankaitis%2C+Vytas+A&rft.au=Grabon%2C+Aby&rft.date=2011-11-15&rft.issn=1534-5807&rft.volume=21&rft.issue=5+p.810-812&rft.spage=810&rft.epage=812&rft_id=info:doi/10.1016%2Fj.devcel.2011.10.016&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1534-5807&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1534-5807&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1534-5807&client=summon