Risk factors for thoracolumbar pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures

• Published in: Journal of international medical research Vol. 49; no. 1; p. 300060521989468
• Main Authors: Fan, Xiaoguang, Li, Sha, Zeng, Xianshang, Yu, Weiguang, Liu, Xiangzhen
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Bone Cements; Fractures; Fractures, Compression - surgery; Humans; Osteoporosis; Osteoporotic Fractures - surgery; Pain; Prospective Studies; Retrospective Clinical Research Report; Retrospective Studies; Risk Factors; Spinal Fractures - diagnostic imaging; Spinal Fractures - surgery; Treatment Outcome; Vertebroplasty - adverse effects; vertebral compression fracture; thoracolumbar pain; Percutaneous vertebroplasty
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/0300060521989468

Objective To explore possible risk factors for poor outcomes following percutaneous vertebroplasty (PV) for painful osteoporotic compression fractures of thoracolumbar vertebra. Methods This was a retrospective review of data from patients who underwent PV at our institution over a ten-year period to evaluate the association between possible risk factors and thoracolumbar pain (T11-L2). According to the difference between pre- and post-operative visual analogue scale (VAS) scores for pain, patients were separated into poor relief (PR; <4) and good relief (GR; ≥4) of pain. Results Of the 750 patients identified, 630 (PR group, n =310; GR group, n = 320) fulfilled the eligibility criteria. Multivariate binary logistic analysis showed that bone mineral density (BMD), >2 fractured vertebral bodies, maldistribution of bone cement, <5 ml bone cement injected into a single vertebral body and thoracolumbar fascia injury prior to surgery were independent risk factors associated with thoracolumbar pain following PV. Conclusion Although prospective controlled studies are required to confirm our results, this review suggests that the above factors should be taken into account when selecting patients for PV.