Pathogenic Strains of Yersinia enterocolitica Isolated from Domestic Dogs (Canis familiaris) Belonging to Farmers Are of the Same Subtype as Pathogenic Y. enterocolitica Strains Isolated from Humans and May Be a Source of Human Infection in Jiangsu Province, China

• Published in: Journal of Clinical Microbiology Vol. 48; no. 5; pp. 1604 - 1610
• Main Authors: Wang, Xin, Cui, Zhigang, Wang, Hua, Tang, Liuying, Yang, Jinchuan, Gu, Ling, Jin, Dong, Luo, Longze, Qiu, Haiyan, Xiao, Yuchun, Xiong, Haiping, Kan, Biao, Xu, Jianguo, Jing, Huaiqi
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.05.2010; American Society for Microbiology (ASM)
• Subjects: Animals; Animals, Domestic - microbiology; Animals, Wild - microbiology; Bacteriology; Biological and medical sciences; Canis familiaris; Carrier State - epidemiology; Carrier State - microbiology; Carrier State - veterinary; China - epidemiology; Cluster Analysis; DNA Fingerprinting; Dog Diseases - epidemiology; Dog Diseases - microbiology; Dogs - microbiology; Electrophoresis, Gel, Pulsed-Field; Environmental Microbiology; Fundamental and applied biological sciences. Psychology; Genotype; Humans; Insecta - microbiology; Microbiology; Miscellaneous; Molecular Epidemiology; Serotyping; Yersinia enterocolitica; Yersinia enterocolitica - classification; Yersinia enterocolitica - isolation & purification; Yersinia Infections - epidemiology; Yersinia Infections - microbiology; Yersinia Infections - veterinary; Asia; China; Human; Fissipedia; Carnivora; Canis familiaris; Strain; Yersinia enterocolitica; Vertebrata; Mammalia; Bacteria; Veterinary; Dog; Subtype; Enterobacteriaceae
• ISSN: 0095-1137; 1098-660X
• DOI: 10.1128/JCM.01789-09

We isolated 326 Yersinia enterocolitica strains from 5,919 specimens from patients with diarrhea at outpatient clinics, livestock, poultry, wild animals, insect vectors, food, and the environment in the cities of Nantong and Xuzhou in Jiangsu Province, China, from 2004 to 2008. The results showed that the 12 pathogenic strains were of the O:3 serotype. Six strains were isolated from domestic dogs (Canis familiaris) belonging to farmers and were found to be the primary carriers of pathogenic Y. enterocolitica strains, especially in Xuzhou. Pulsed-field gel electrophoresis analysis of the pathogenic strains from dogs belonging to farmers showed that they shared the same patterns as strains from diarrhea patients isolated in 1994. This indicates that the strains from domestic dogs have a close correlation with the strains causing human infections.