Embryonal rhabdomyosarcoma within abdomen and pelvis in an adult

• Published in: International journal of immunopathology and pharmacology Vol. 32; p. 2058738418806728
• Main Authors: Hao, Zhimin, Yang, Sufen
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2018; Sage Publications Ltd
• Subjects: Abdomen; Abdominal Neoplasms - chemistry; Abdominal Neoplasms - diagnostic imaging; Abdominal Neoplasms - pathology; Abdominal Neoplasms - therapy; Biomarkers, Tumor - analysis; Biopsy; Chemotherapy, Adjuvant; Cytoreduction Surgical Procedures; Female; Gynecology; Humans; Immunohistochemistry; Letter to the Editor; Magnetic Resonance Imaging; Middle Aged; Neoplasm Recurrence, Local; Pelvic Neoplasms - chemistry; Pelvic Neoplasms - diagnostic imaging; Pelvic Neoplasms - pathology; Pelvic Neoplasms - therapy; Rhabdomyosarcoma; Rhabdomyosarcoma, Embryonal - chemistry; Rhabdomyosarcoma, Embryonal - diagnostic imaging; Rhabdomyosarcoma, Embryonal - pathology; Rhabdomyosarcoma, Embryonal - therapy; Sarcoma; Time Factors; Treatment Outcome; Tumor Burden; leiomyosarcoma; embryonal; rhabdomyosarcoma; soft tissue sarcoma; abdominopelvic
• ISSN: 0394-6320; 2058-7384
• DOI: 10.1177/2058738418806728

Rhabdomyosarcoma arising in abdomen and pelvis is an uncommon but important type of soft tissue sarcoma, posing a great challenge for clinicians. Sporadic cases of intra-abdominal rhabdomyosarcoma were reported, but mostly in pediatrics. We demonstrated a rare case of primary abdominopelvic rhabdomyosarcoma in an elderly woman who presented with a notable increase in abdominal circumference and constipation. Abdominal magnetic resonance imaging showed a huge mass throughout the abdomen and pelvis. Cytoreductive surgery was performed by gynecologists due to the suspicious diagnosis of disseminated leiomyosarcoma. However, the final pathological analysis revealed embryonal rhabdomyosarcoma. Although adjuvant chemotherapy was administered, localized recurrence was identified 6 months after the initial operation. Gynecologists and radiologists should be aware of it so it can be listed in the differential diagnosis of masses that primarily arise in the abdomen and pelvis.