Aspiration cytology of neuroblastoma: Light and electron microscopic correlations

Fine‐needle aspiration biopsy (FNAB) smears from 16 cases of neuroblastoma are reviewed, and various cytomorphologic features helpful in diagnosing this tumor are described. Cytoplasmic processes were present in ten cases, and pseudorosettes in three cases. Electron microscopic study of FNAB samples...

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Published inCancer Vol. 57; no. 4; pp. 797 - 803
Main Authors Akhtar, Mohammed, Ali, M. Ashraf, Sabbah, Rajeh S., Bakry, Mohamed, Sackey, Kwesi, Nash, Elinor J.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 15.02.1986
Wiley-Liss
Subjects
Biological and medical sciences
Biopsy, Needle
Child
Child, Preschool
Cytoplasm - ultrastructure
Female
Humans
Infant
Male
Medical sciences
Microscopy, Electron
Neuroblastoma - pathology
Neuroblastoma - ultrastructure
Neurology
Tumors of the nervous system. Phacomatoses
Human
Optical microscopy
Nervous system diseases
Aspiration
Biopsy
Cytologic investigation
Diagnostic
Tumor
Neuroblastoma
Electron microscopy
Child
Tumor cell
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Summary:Fine‐needle aspiration biopsy (FNAB) smears from 16 cases of neuroblastoma are reviewed, and various cytomorphologic features helpful in diagnosing this tumor are described. Cytoplasmic processes were present in ten cases, and pseudorosettes in three cases. Electron microscopic study of FNAB samples revealed that all diagnostically important features, such as cell processes, neurosecretory granules, and synaptic cell junctions, could be recognized. These findings indicate that FNAB studied by light and electron microscopy is an effective method for diagnosing neuroblastoma.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19860215)57:4<797::AID-CNCR2820570419>3.0.CO;2-A