Biomaterials and scaffolds for ligament tissue engineering

Tissue engineering has achieved much progress in an attempt to improve and recover impaired functions of tissues and organs. Although many studies have been done, progress for tissue‐engineered anterior cruciate ligaments (ACLs) has been slow due to their complex structures and mechanical properties...

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Published inJournal of biomedical materials research. Part A Vol. 77A; no. 3; pp. 639 - 652
Main Authors Ge, Zigang, Yang, Fang, Goh, James C. H., Ramakrishna, Seeram, Lee, Eng Hin
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2006
Subjects
Biocompatible Materials
biomaterials availability
ligament
Ligaments
polymer
scaffolds
Tissue Engineering
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Summary:Tissue engineering has achieved much progress in an attempt to improve and recover impaired functions of tissues and organs. Although many studies have been done, progress for tissue‐engineered anterior cruciate ligaments (ACLs) has been slow due to their complex structures and mechanical properties. In this review, the ACL anatomical structure, progresses achieved, material selection, structure design, and future direction have been discussed, while the challenges and requirements from materials and scaffolds are highlighted. There is a considerably huge amount work that needs to be carried out; as such, future direction in ligament tissue engineering is proposed in hope that this review will give information on future ligament tissue engineering. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res 2006
Bibliography:ark:/67375/WNG-QV83J02P-2
Biomedical Research Council, Singapore
ArticleID:JBM30578
istex:50D8DDCAB46CC88928A4BB96C3271ACCF7532454
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Feature-3
ObjectType-Review-1
ISSN:1549-3296
1552-4965
DOI:10.1002/jbm.a.30578