Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain

Highlights • Translational landscape in DRG and spinal cord in SNI assay of neuropathic pain was established. • ERK is a central hub of both transcriptionally and translationally controlled genes. • Changes in translation efficiency and mRNA levels occur in the opposite direction for multiple mRNAs....

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Published inNeurobiology of pain Vol. 4; pp. 35 - 44
Main Authors Uttam, Sonali, Wong, Calvin, Amorim, Inês S, Jafarnejad, Seyed Mehdi, Tansley, Shannon N, Yang, Jieyi, Prager-Khoutorsky, Masha, Mogil, Jeffrey S, Gkogkas, Christos G, Khoutorsky, Arkady
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.08.2018
Elsevier
Subjects
Original Research
Pain Medicine
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Summary:Highlights • Translational landscape in DRG and spinal cord in SNI assay of neuropathic pain was established. • ERK is a central hub of both transcriptionally and translationally controlled genes. • Changes in translation efficiency and mRNA levels occur in the opposite direction for multiple mRNAs.
Bibliography:ObjectType-Article-1
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These authors contributed equally to this manuscript.
ISSN:2452-073X
2452-073X
DOI:10.1016/j.ynpai.2018.04.001