Shape-memory anchoring system for bladder sensors

• Published in: Journal of biomedical materials research. Part B, Applied biomaterials Vol. 96B; no. 2; pp. 369 - 375
• Main Authors: Pereira, Iaci M., Axisa, Fabrice, Oréfice, Rodrigo L., Vanfleteren, Jan, Neves, Hercules P.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.02.2011; Wiley-Blackwell
• Subjects: Anchoring; Biocompatible Materials - therapeutic use; biodegradable waterborne; Biological and medical sciences; Biomedical materials; Bladder; bladder sensor; Diagnostic Equipment; Electric Impedance - therapeutic use; Equipment Design; Materials Testing; Medical sciences; Models, Biological; Polyurethanes - therapeutic use; Recovery; Segments; Sensors; shape-memory; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgical implants; Technology. Biomaterials. Equipments; Temperature; Urinary Bladder - physiology; Urine; shape-memory; Urinary system; Urinary bladder; biodegradable waterborne; Memory; bladder sensor; Biomaterial; Anchoring; Biomedical engineering
• ISSN: 1552-4973; 1552-4981; 1552-4981
• DOI: 10.1002/jbm.b.31780

In this work, we propose the use of shape‐memory polymer as an anchoring system for a bladder sensor. The anchoring system was designed from a biomedical biodegradable water‐based poly(ester‐urethane) produced in an aqueous environment by using isophorone diisocyanate/hydrazine (hard segment) and poly(caprolactone diol)/2,2‐bis (hydroxymethyl) propionic acid (soft segment) as the main reagents. Tensile strength and elongation‐at‐break deterioration upon degradation in synthetic urine were investigated. In‐body shape recovery was simulated and measured in synthetic urine. Results indicated that shape recovery can occur at body temperature and expulsion of the sensor by the body along with urine may occur through the combined effect of urine hydrolytic attack and compression exerted by the bladder walls. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2011.