Recent Progress on Solid Substrates for Surface-Enhanced Raman Spectroscopy Analysis

Surface-enhanced Raman spectroscopy (SERS) is a powerful vibrational spectroscopy technique with distinguished features of non-destructivity, ultra-sensitivity, rapidity, and fingerprint characteristics for analysis and sensors. The SERS signals are mainly dependent on the engineering of high-qualit...

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Published inBiosensors (Basel) Vol. 12; no. 11; p. 941
Main Authors Ge, Kun, Hu, Yuling, Li, Gongke
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 30.10.2022
MDPI
Subjects
Analysis
applications
Cellulose
construction
Control stability
Controllability
Electric fields
Fabrication
Fingerprints
Food safety
Health aspects
Metals
Methods
Morphology
Nanoparticles
perspectives
Raman spectroscopy
Review
Self-assembly
Semiconductors
solid substrate
Spectroscopy
Spectrum analysis
Substrates
surface-enhanced Raman spectroscopy
China
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Summary:Surface-enhanced Raman spectroscopy (SERS) is a powerful vibrational spectroscopy technique with distinguished features of non-destructivity, ultra-sensitivity, rapidity, and fingerprint characteristics for analysis and sensors. The SERS signals are mainly dependent on the engineering of high-quality substrates. Recently, solid SERS substrates with diverse forms have been attracting increasing attention due to their promising features, including dense hot spot, high stability, controllable morphology, and convenient portability. Here, we comprehensively review the recent advances made in the field of solid SERS substrates, including their common fabrication methods, basic categories, main features, and representative applications, respectively. Firstly, the main categories of solid SERS substrates, mainly including membrane substrate, self-assembled substrate, chip substrate, magnetic solid substrate, and other solid substrate, are introduced in detail, as well as corresponding construction strategies and main features. Secondly, the typical applications of solid SERS substrates in bio-analysis, food safety analysis, environment analysis, and other analyses are briefly reviewed. Finally, the challenges and perspectives of solid SERS substrates, including analytical performance improvement and largescale production level enhancement, are proposed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:2079-6374
2079-6374
DOI:10.3390/bios12110941