Pulmonary Valve Replacement With Fresh Decellularized Pulmonary Allograft for Pulmonary Regurgitation After Tetralogy of Fallot Repair　– First Case Report in Japan

• Published in: Circulation Journal Vol. 80; no. 4; pp. 1041 - 1043
• Main Authors: Ueno, Takayoshi, Ozawa, Hideto, Taira, Masaki, Kanaya, Tomomitsu, Toda, Koichi, Kuratani, Toru, Sawa, Yoshiki
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Circulation Society 2016
• Subjects: Adult; Decellularized pulmonary allograft; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Male; Pulmonary Valve - surgery; Pulmonary Valve Insufficiency - complications; Pulmonary Valve Insufficiency - surgery; Pulmonary valve regurgitation; Pulmonary valve replacement; Tetralogy of Fallot; Tetralogy of Fallot - complications; Tetralogy of Fallot - surgery
• ISSN: 1346-9843; 1347-4820
• DOI: 10.1253/circj.CJ-15-0973

Background:Pulmonary valve replacement (PVR) is a common reoperation, typically required approximately 10 years following right ventricular outflow tract reconstruction and especially true in cases of tetralogy of Fallot. However, an improved prosthetic valve is required.Methods and Results:A fresh decellularized pulmonary allograft was used for PVR to correct pulmonary valve regurgitation in a 35-year-old man 33 years following tetralogy of Fallot repair. The postoperative course and short-term valve function were excellent. This is the first case of a decellularized pulmonary allograft in Japan.Conclusions:Fresh decellularized pulmonary allografts have the potential to become a new source of material for PVR in patients who have undergone right ventricular outflow tract reconstruction. (Circ J 2016; 80: 1041–1043)