Lobomycosis

Lobomycosis is a rare chronic fungal infection of the subcutaneous tissue found in South America, mainly in Brazil. It is caused by Lacazia loboi. Its clinical manifestations are dermal nodules, either lenticular or in plaques, and keloidlike lesions that can resemble nodular leprosy or leishmaniasi...

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Published inClinics in dermatology Vol. 30; no. 4; pp. 420 - 424
Main Authors Talhari, Sinésio, Talhari, Carolina
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2012
Subjects
Antifungal Agents - therapeutic use
Clofazimine - therapeutic use
Dermatology
Diagnosis, Differential
Female
Humans
Itraconazole - therapeutic use
Lacazia - isolation & purification
Leprostatic Agents - therapeutic use
Lobomycosis - drug therapy
Lobomycosis - pathology
Male
Prognosis
Sex Factors
South America
Treatment Outcome
South America
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Summary:Lobomycosis is a rare chronic fungal infection of the subcutaneous tissue found in South America, mainly in Brazil. It is caused by Lacazia loboi. Its clinical manifestations are dermal nodules, either lenticular or in plaques, and keloidlike lesions that can resemble nodular leprosy or leishmaniasis, other subcutaneous mycoses (sporotrychosis, chromomycosis, paracoccidioidomycosis), keloids, and malignant tumors. Diagnosis is made by the histopathological findings of the fungus. For treatment, surgical removal of the lesions, followed by itraconazole and clofazimine for disseminated lesions, has been used with variable results.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0738-081X
1879-1131
1879-1131
DOI:10.1016/j.clindermatol.2011.09.014