Easy Passage: Germline Transgenesis in Frogs

Amphibians have been a favored model organism for studies of early development for over a century. The African frog Xenopus laevis's embryos are large and accessible for manipulation from fertilization onward.

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Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 96; no. 25; pp. 14189 - 14190
Main Authors Kroll, Kristen L., Kirschner, Marc W.
Format Journal Article
LanguageEnglish
Published United States National Academy of Sciences of the United States of America 07.12.1999
National Acad Sciences
National Academy of Sciences
The National Academy of Sciences
Subjects
Animals
Cellular biology
Commentaries
Embryology
Embryonic cells
Embryos
Frogs
Gene transfer techniques
Ova
Plasmids
Promoter Regions, Genetic
Reptiles & amphibians
Ribonucleic acid
RNA
Spermatozoa
Transgenes
Transgenic animals
Vertebrates
Xenopus laevis - genetics
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Summary:Amphibians have been a favored model organism for studies of early development for over a century. The African frog Xenopus laevis's embryos are large and accessible for manipulation from fertilization onward.
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To whom reprint requests should be addressed. E-mail: kkroll@bcmp.med.harvard.edu.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.96.25.14189