Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial
Aim To compare the effect of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. Methods Twenty‐four subjects were enrolled in a randomized, controlled, parall...
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| Published in | Journal of clinical periodontology Vol. 40; no. 10; pp. 968 - 975 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Blackwell Publishing Ltd
01.10.2013
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Aim
To compare the effect of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.
Methods
Twenty‐four subjects were enrolled in a randomized, controlled, parallel‐group, open‐label clinical trial. Subjects either received rhBMP‐2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium‐mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone‐beam computed tomography.
Results
rhBMP‐2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non‐significant differences were observed at mid‐ (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP‐2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty‐two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival.
Conclusions
rhBMP‐2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla.
View the pubcast on this paper at http://www.scivee.tv/journalnode/60739 |
|---|---|
| AbstractList | Aim
To compare the effect of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.
Methods
Twenty‐four subjects were enrolled in a randomized, controlled, parallel‐group, open‐label clinical trial. Subjects either received rhBMP‐2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium‐mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone‐beam computed tomography.
Results
rhBMP‐2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non‐significant differences were observed at mid‐ (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP‐2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty‐two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival.
Conclusions
rhBMP‐2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla.
View the pubcast on this paper at http://www.scivee.tv/journalnode/60739 Aim To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. Methods Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography. Results rhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival. Conclusions rhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla. [PUBLICATION ABSTRACT] To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography. rhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival. rhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla. To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography. rhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 plus or minus 0.7 versus 0.5 plus or minus 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 plus or minus 0.8 versus 2.9 plus or minus 0.9 mm; p = 0.98) and apical (1.7 plus or minus 0.9 versus 1.8 plus or minus 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 plus or minus 0.9 mm versus 3.7 plus or minus 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival. rhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla. To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.AIMTo compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography.METHODSTwenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography.rhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival.RESULTSrhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival.rhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla.CONCLUSIONSrhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla. View the pubcast on this paper at http://www.scivee.tv/journalnode/60739 |
| Author | Spin-Neto, Rubens Pereira, Luís Antônio Violin Dias de Freitas, Rubens Moreno Marcantonio Jr, Elcio Susin, Cristiano Wikesjö, Ulf M. E. Marcantonio, Claudio |
| Author_xml | – sequence: 1 givenname: Rubens Moreno surname: de Freitas fullname: de Freitas, Rubens Moreno organization: Department of Diagnosis and Surgery - Periodontics, UNESP - Univ Estadual Paulista, Araraquara Dental School, Araraquara, SP, Brazil – sequence: 2 givenname: Cristiano surname: Susin fullname: Susin, Cristiano organization: Laboratory for Applied Periodontal & Craniofacial Regeneration, Departments of Periodontics and Oral Biology, College of Dental Medicine, Augusta, GA, USA – sequence: 3 givenname: Rubens surname: Spin-Neto fullname: Spin-Neto, Rubens organization: Department of Diagnosis and Surgery - Periodontics, UNESP - Univ Estadual Paulista, Araraquara Dental School, Araraquara, SP, Brazil – sequence: 4 givenname: Claudio surname: Marcantonio fullname: Marcantonio, Claudio organization: Department of Diagnosis and Surgery - Periodontics, UNESP - Univ Estadual Paulista, Araraquara Dental School, SP, Araraquara, Brazil – sequence: 5 givenname: Ulf M. E. surname: Wikesjö fullname: Wikesjö, Ulf M. E. organization: Laboratory for Applied Periodontal & Craniofacial Regeneration, Departments of Periodontics and Oral Biology, College of Dental Medicine, Augusta, GA, USA – sequence: 6 givenname: Luís Antônio Violin Dias surname: Pereira fullname: Pereira, Luís Antônio Violin Dias organization: Department of Histology and Embryology, UNICAMP - State University of Campinas, Institute of Biology, SP, Campinas, Brazil – sequence: 7 givenname: Elcio surname: Marcantonio Jr fullname: Marcantonio Jr, Elcio email: Address:Elcio Marcantonio JrDepartment of Diagnosis and Surgery - PeriodonticsUNESP - Univ Estadual Paulista, Araraquara Dental SchoolRua Humaitá, 1680 - 2nd floorAraraquara, SP, Brazil 14801-903, elciojr@foar.unesp.br organization: Department of Diagnosis and Surgery - Periodontics, UNESP - Univ Estadual Paulista, Araraquara Dental School, SP, Araraquara, Brazil |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23998375$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/j.1601-6343.2009.01461.x 10.1016/j.joms.2005.08.018 10.1016/j.joms.2007.11.021 10.1902/jop.1997.68.12.1186 10.1016/j.joms.2007.06.670 10.1007/s00264-007-0418-6 10.1902/jop.2000.71.8.1241 10.1902/jop.2012.110369 10.1016/j.joms.2009.04.085 10.1002/14651858.CD003878.pub4 10.1111/j.1600-0501.2008.01648.x 10.1902/jop.2005.76.4.605 10.1097/ID.0b013e3181bd0c7c 10.1016/j.joms.2008.01.058 10.1111/j.1600-0501.2004.00971.x 10.1111/j.1708-8208.2003.tb00192.x 10.1111/jcpe.12109 10.1034/j.1600-0501.2003.00921.x 10.1111/j.1600-0501.2011.02419.x |
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| Keywords | randomized-controlled trial recombinant human bone morphogenetic protein rhBMP-2 alveolar ridge augmentation autogenous bone graft |
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| Notes | istex:93B8437DF9B0666D9A58569F214B1EC74C453FA3 ArticleID:JCPE12148 Nobel Biocare AB ark:/67375/WNG-TWX8H5K2-W São Paulo Research Foundation - No. 2009/16016-8 3M Non-Tenured Faculty Conflict of interest and source of funding statement The authors declare no conflict of interest for this study. Research funding was provided from the São Paulo Research Foundation (FAPESP – grant number 2009/16016‐8), São Paulo, Brazil and CAPES, Brasilia, Brazil. Dr. Susin was supported in part by a 3M Non‐Tenured Faculty Grant, St Paul, MN, USA. Drs Wikesjö and Susin were supported in part by a grant from Nobel Biocare AB, Göteborg, Sweden. SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-2 content type line 23 ObjectType-Undefined-3 |
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| References | Jung, R. E., Glauser, R., Scharer, P., Hammerle, C. H., Sailer, H. F. & Weber, F. E. (2003) Effect of rhBMP-2 on guided bone regeneration in humans. Clinical Oral Implants Research 14, 556-568. Jung, R. E., Windisch, S. I., Eggenschwiler, A. M., Thoma, D. S., Weber, F. E. & Hammerle, C. H. (2009) A randomized-controlled clinical trial evaluating clinical and radiological outcomes after 3 and 5 years of dental implants placed in bone regenerated by means of GBR techniques with or without the addition of BMP-2. Clinical Oral Implants Research 20, 660-666. Lee, J., Lee, E. N., Yoon, J., Chung, S.-M., Prasad, H., Susin, C. & Wikesjö, U. M. E. (2013b) Comparative study of Chinese Hamster Ovary cell- versus Escherichia coli-derived bone morphogenetic protein-2 using the critical-size supraalveolar peri-implant defect model. Journal of Periodontology 84, 415-422. Boyne, P. J., Lilly, L. C., Marx, R. E., Moy, P. K., Nevins, M., Spagnoli, D. B. & Triplett, R. G. (2005) De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation. Journal of Oral and Maxillofacial Surgery 63, 1693-1707. Howell, T. H., Fiorellini, J., Jones, A., Alder, M., Nummikoski, P., Lazaro, M., Lilly, L. & Cochran, D. (1997) A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation. International Journal of Periodontics and Restorative Dentistry 17, 124-139. Wikesjö, U. M. E., Qahash, M., Huang, Y. H., Xiropaidis, A., Polimeni, G. & Susin, C. (2009) Bone morphogenetic proteins for periodontal and alveolar indications; biological observations - clinical implications. Orthodontics and Craniofacial Research 12, 263-270. Triplett, R. G., Nevins, M., Marx, R. E., Spagnoli, D. B., Oates, T. W., Moy, P. K. & Boyne, P. J. (2009) Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation. Journal of Oral and Maxillofacial Surgery 67, 1947-1960. Spin-Neto, R., Bedran, T. B., de Paula, W. N., de Freitas, R. M., de Oliveira Ramalho, L. T. & Marcantonio, E. Jr (2009) Incisive canal deflation for correct implant placement: case report. Implant Dentistry 18, 473-479. Wikesjö, U. M. E., Qahash, M., Thomson, R. C., Cook, A. D., Rohrer, M. D., Wozney, J. M. & Hardwick, W. R. (2003) Space-providing expanded polytetrafluoroethylene devices define alveolar augmentation at dental implants induced by recombinant human bone morphogenetic protein 2. Clinical Implant Dentistry and Related Research 5, 112-123. Herford, A. S. & Boyne, P. J. (2008) Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). Journal of Oral and Maxillofacial Surgery 66, 616-624. Carter, T. G., Brar, P. S., Tolas, A. & Beirne, O. R. (2008) Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. Journal of Oral and Maxillofacial Surgery 66, 1417-1425. Boyne, P. J., Marx, R. E., Nevins, M., Triplett, G., Lazaro, E., Lilly, L. C., Alder, M. & Nummikoski, P. (1997) A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation. International Journal of Periodontics and Restorative Dentistry 17, 11-25. McKay, W. F., Peckham, S. M. & Badura, J. M. (2007) A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE® Bone Graft). International Orthopaedics 31, 729-734. Misch, C. M. (2011) Bone augmentation of the atrophic posterior mandible for dental implants using rhBMP-2 and titanium mesh: clinical technique and early results. International Journal of Periodontics and Restorative Dentistry 31, 581-589. Cochran, D. L., Jones, A. A., Lilly, L. C., Fiorellini, J. P. & Howell, H. (2000) Evaluation of recombinant human bone morphogenetic protein-2 in oral applications including the use of endosseous implants: 3-year results of a pilot study in humans. Journal of Periodontology 71, 1241-1257. Esposito, M., Grusovin, M. G., Kwan, S., Worthington, H. V. & Coulthard, P. (2009a) Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment. Cochrane Database Systematic Review 16, CD003607. Review. Update in: Cochrane Database Syst Rev 2009,(4):CD003607. Kao, D. W., Kubota, A., Nevins, M. & Fiorellini, J. P. (2012) The negative effect of combining rhBMP-2 and Bio-Oss on bone formation for maxillary sinus augmentation. International Journal of Periodontics and Restorative Dentistry 32, 61-67. Esposito, M., Grusovin, M. G., Felice, P., Karatzopoulos, G., Worthington, H. V. & Coulthard, P. (2009b) Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment. Cochrane Database Systematic Review 7, CD003607. Wikesjö, U. M. E., Qahash, M., Thomson, R. C., Cook, A. D., Rohrer, M. D., Wozney, J. M. & Hardwick, W. R. (2004) rhBMP-2 significantly enhances guided bone regeneration. Clinical Oral Implants Research 15, 194-204. Fiorellini, J. P., Howell, T. H., Cochran, D., Malmquist, J., Lilly, L. C., Spagnoli, D., Toljanic, J., Jones, A. & Nevins, M. (2005) Randomized study evaluating recombinant human bone morphogenetic protein-2 for extraction socket augmentation. Journal of Periodontology 76, 605-613. Herford, A. S., Boyne, P. J., Rawson, R. & Williams, R. P. (2007) Bone morphogenetic protein-induced repair of the premaxillary cleft. Journal of Oral and Maxillofacial Surgery 65, 2136-2141. Lu, S. X., Fiorini, T., Lee, J., Prasad, H. S., Buxton, A. N., Bisch, F. C., Dixon, D. R., Susin, C. & Wikesjö, U. M. E. (2013) Evaluation of a compression resistant carrier for recombinant human bone morphogenetic protein-2. Journal of Clinical Periodontology 40, 688-697. Lee, J., Susin, C., Rodriguez, N. A., de Stefano, J., Prasad, H. S., Buxton, A. N. & Wikesjö, U. M. E. (2013a) Sinus augmentation using rhBMP-2/ACS in a mini-pig model: relative efficacy of autogenous fresh particulate iliac bone grafts. Clinical Oral Implants Research 24, 497-504. 2009; 67 2009; 12 2009; 20 2009b; 7 2013a; 24 2013; 40 2013b; 84 2004; 15 2011; 31 2005; 63 2003; 14 1997; 17 2000; 71 2009a; 16 2005; 76 2003; 5 2008; 66 2007; 31 2007; 65 2012; 32 2009; 18 Esposito M. (e_1_2_14_6_1) 2009; 7 e_1_2_14_2_1 e_1_2_14_20_1 e_1_2_14_4_1 e_1_2_14_3_1 e_1_2_14_11_1 e_1_2_14_23_1 Esposito M. (e_1_2_14_7_1) 2009; 16 e_1_2_14_10_1 e_1_2_14_24_1 e_1_2_14_13_1 Kao D. W. (e_1_2_14_14_1) 2012; 32 e_1_2_14_21_1 e_1_2_14_12_1 e_1_2_14_22_1 e_1_2_14_15_1 e_1_2_14_17_1 e_1_2_14_16_1 e_1_2_14_18_1 Misch C. M. (e_1_2_14_19_1) 2011; 31 e_1_2_14_5_1 e_1_2_14_8_1 e_1_2_14_9_1 |
| References_xml | – reference: Fiorellini, J. P., Howell, T. H., Cochran, D., Malmquist, J., Lilly, L. C., Spagnoli, D., Toljanic, J., Jones, A. & Nevins, M. (2005) Randomized study evaluating recombinant human bone morphogenetic protein-2 for extraction socket augmentation. Journal of Periodontology 76, 605-613. – reference: Lu, S. X., Fiorini, T., Lee, J., Prasad, H. S., Buxton, A. N., Bisch, F. C., Dixon, D. R., Susin, C. & Wikesjö, U. M. E. (2013) Evaluation of a compression resistant carrier for recombinant human bone morphogenetic protein-2. Journal of Clinical Periodontology 40, 688-697. – reference: Cochran, D. L., Jones, A. A., Lilly, L. C., Fiorellini, J. P. & Howell, H. (2000) Evaluation of recombinant human bone morphogenetic protein-2 in oral applications including the use of endosseous implants: 3-year results of a pilot study in humans. Journal of Periodontology 71, 1241-1257. – reference: Lee, J., Lee, E. N., Yoon, J., Chung, S.-M., Prasad, H., Susin, C. & Wikesjö, U. M. E. (2013b) Comparative study of Chinese Hamster Ovary cell- versus Escherichia coli-derived bone morphogenetic protein-2 using the critical-size supraalveolar peri-implant defect model. Journal of Periodontology 84, 415-422. – reference: Boyne, P. J., Marx, R. E., Nevins, M., Triplett, G., Lazaro, E., Lilly, L. C., Alder, M. & Nummikoski, P. (1997) A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation. International Journal of Periodontics and Restorative Dentistry 17, 11-25. – reference: Triplett, R. G., Nevins, M., Marx, R. E., Spagnoli, D. B., Oates, T. W., Moy, P. K. & Boyne, P. J. (2009) Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation. Journal of Oral and Maxillofacial Surgery 67, 1947-1960. – reference: Kao, D. W., Kubota, A., Nevins, M. & Fiorellini, J. P. (2012) The negative effect of combining rhBMP-2 and Bio-Oss on bone formation for maxillary sinus augmentation. International Journal of Periodontics and Restorative Dentistry 32, 61-67. – reference: Spin-Neto, R., Bedran, T. B., de Paula, W. N., de Freitas, R. M., de Oliveira Ramalho, L. T. & Marcantonio, E. Jr (2009) Incisive canal deflation for correct implant placement: case report. Implant Dentistry 18, 473-479. – reference: Misch, C. M. (2011) Bone augmentation of the atrophic posterior mandible for dental implants using rhBMP-2 and titanium mesh: clinical technique and early results. International Journal of Periodontics and Restorative Dentistry 31, 581-589. – reference: McKay, W. F., Peckham, S. M. & Badura, J. M. (2007) A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE® Bone Graft). International Orthopaedics 31, 729-734. – reference: Herford, A. S., Boyne, P. J., Rawson, R. & Williams, R. P. (2007) Bone morphogenetic protein-induced repair of the premaxillary cleft. Journal of Oral and Maxillofacial Surgery 65, 2136-2141. – reference: Wikesjö, U. M. E., Qahash, M., Huang, Y. H., Xiropaidis, A., Polimeni, G. & Susin, C. (2009) Bone morphogenetic proteins for periodontal and alveolar indications; biological observations - clinical implications. Orthodontics and Craniofacial Research 12, 263-270. – reference: Esposito, M., Grusovin, M. G., Kwan, S., Worthington, H. V. & Coulthard, P. (2009a) Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment. Cochrane Database Systematic Review 16, CD003607. Review. Update in: Cochrane Database Syst Rev 2009,(4):CD003607. – reference: Jung, R. E., Glauser, R., Scharer, P., Hammerle, C. H., Sailer, H. F. & Weber, F. E. (2003) Effect of rhBMP-2 on guided bone regeneration in humans. Clinical Oral Implants Research 14, 556-568. – reference: Howell, T. H., Fiorellini, J., Jones, A., Alder, M., Nummikoski, P., Lazaro, M., Lilly, L. & Cochran, D. (1997) A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation. International Journal of Periodontics and Restorative Dentistry 17, 124-139. – reference: Esposito, M., Grusovin, M. G., Felice, P., Karatzopoulos, G., Worthington, H. V. & Coulthard, P. (2009b) Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment. Cochrane Database Systematic Review 7, CD003607. – reference: Lee, J., Susin, C., Rodriguez, N. A., de Stefano, J., Prasad, H. S., Buxton, A. N. & Wikesjö, U. M. E. (2013a) Sinus augmentation using rhBMP-2/ACS in a mini-pig model: relative efficacy of autogenous fresh particulate iliac bone grafts. Clinical Oral Implants Research 24, 497-504. – reference: Wikesjö, U. M. E., Qahash, M., Thomson, R. C., Cook, A. D., Rohrer, M. D., Wozney, J. M. & Hardwick, W. R. (2004) rhBMP-2 significantly enhances guided bone regeneration. Clinical Oral Implants Research 15, 194-204. – reference: Jung, R. E., Windisch, S. I., Eggenschwiler, A. M., Thoma, D. S., Weber, F. E. & Hammerle, C. H. (2009) A randomized-controlled clinical trial evaluating clinical and radiological outcomes after 3 and 5 years of dental implants placed in bone regenerated by means of GBR techniques with or without the addition of BMP-2. Clinical Oral Implants Research 20, 660-666. – reference: Wikesjö, U. M. E., Qahash, M., Thomson, R. C., Cook, A. D., Rohrer, M. D., Wozney, J. M. & Hardwick, W. R. (2003) Space-providing expanded polytetrafluoroethylene devices define alveolar augmentation at dental implants induced by recombinant human bone morphogenetic protein 2. Clinical Implant Dentistry and Related Research 5, 112-123. – reference: Herford, A. S. & Boyne, P. J. (2008) Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). Journal of Oral and Maxillofacial Surgery 66, 616-624. – reference: Boyne, P. J., Lilly, L. C., Marx, R. E., Moy, P. K., Nevins, M., Spagnoli, D. B. & Triplett, R. G. (2005) De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation. Journal of Oral and Maxillofacial Surgery 63, 1693-1707. – reference: Carter, T. G., Brar, P. S., Tolas, A. & Beirne, O. R. (2008) Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. Journal of Oral and Maxillofacial Surgery 66, 1417-1425. – volume: 66 start-page: 616 year: 2008 end-page: 624 article-title: Reconstruction of mandibular continuity defects with bone morphogenetic protein‐2 (rhBMP‐2) publication-title: Journal of Oral and Maxillofacial Surgery – volume: 84 start-page: 415 year: 2013b end-page: 422 article-title: Comparative study of Chinese Hamster Ovary cell‐ versus Escherichia coli‐derived bone morphogenetic protein‐2 using the critical‐size supraalveolar peri‐implant defect model publication-title: Journal of Periodontology – volume: 65 start-page: 2136 year: 2007 end-page: 2141 article-title: Bone morphogenetic protein‐induced repair of the premaxillary cleft publication-title: Journal of Oral and Maxillofacial Surgery – volume: 24 start-page: 497 year: 2013a end-page: 504 article-title: Sinus augmentation using rhBMP‐2/ACS in a mini‐pig model: relative efficacy of autogenous fresh particulate iliac bone grafts publication-title: Clinical Oral Implants Research – volume: 76 start-page: 605 year: 2005 end-page: 613 article-title: Randomized study evaluating recombinant human bone morphogenetic protein‐2 for extraction socket augmentation publication-title: Journal of Periodontology – volume: 40 start-page: 688 year: 2013 end-page: 697 article-title: Evaluation of a compression resistant carrier for recombinant human bone morphogenetic protein‐2 publication-title: Journal of Clinical Periodontology – volume: 66 start-page: 1417 year: 2008 end-page: 1425 article-title: Off‐label use of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) for reconstruction of mandibular bone defects in humans publication-title: Journal of Oral and Maxillofacial Surgery – volume: 16 year: 2009a article-title: Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment publication-title: Cochrane Database Systematic Review – volume: 31 start-page: 581 year: 2011 end-page: 589 article-title: Bone augmentation of the atrophic posterior mandible for dental implants using rhBMP‐2 and titanium mesh: clinical technique and early results publication-title: International Journal of Periodontics and Restorative Dentistry – volume: 18 start-page: 473 year: 2009 end-page: 479 article-title: Incisive canal deflation for correct implant placement: case report publication-title: Implant Dentistry – volume: 67 start-page: 1947 year: 2009 end-page: 1960 article-title: Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein‐2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation publication-title: Journal of Oral and Maxillofacial Surgery – volume: 17 start-page: 11 year: 1997 end-page: 25 article-title: A feasibility study evaluating rhBMP‐2/absorbable collagen sponge for maxillary sinus floor augmentation publication-title: International Journal of Periodontics and Restorative Dentistry – volume: 7 year: 2009b article-title: Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment publication-title: Cochrane Database Systematic Review – volume: 20 start-page: 660 year: 2009 end-page: 666 article-title: A randomized‐controlled clinical trial evaluating clinical and radiological outcomes after 3 and 5 years of dental implants placed in bone regenerated by means of GBR techniques with or without the addition of BMP‐2 publication-title: Clinical Oral Implants Research – volume: 32 start-page: 61 year: 2012 end-page: 67 article-title: The negative effect of combining rhBMP‐2 and Bio‐Oss on bone formation for maxillary sinus augmentation publication-title: International Journal of Periodontics and Restorative Dentistry – volume: 71 start-page: 1241 year: 2000 end-page: 1257 article-title: Evaluation of recombinant human bone morphogenetic protein‐2 in oral applications including the use of endosseous implants: 3‐year results of a pilot study in humans publication-title: Journal of Periodontology – volume: 63 start-page: 1693 year: 2005 end-page: 1707 article-title: De novo bone induction by recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in maxillary sinus floor augmentation publication-title: Journal of Oral and Maxillofacial Surgery – volume: 31 start-page: 729 year: 2007 end-page: 734 article-title: A comprehensive clinical review of recombinant human bone morphogenetic protein‐2 (INFUSE® Bone Graft) publication-title: International Orthopaedics – volume: 15 start-page: 194 year: 2004 end-page: 204 article-title: rhBMP‐2 significantly enhances guided bone regeneration publication-title: Clinical Oral Implants Research – volume: 14 start-page: 556 year: 2003 end-page: 568 article-title: Effect of rhBMP‐2 on guided bone regeneration in humans publication-title: Clinical Oral Implants Research – volume: 12 start-page: 263 year: 2009 end-page: 270 article-title: Bone morphogenetic proteins for periodontal and alveolar indications; biological observations ‐ clinical implications publication-title: Orthodontics and Craniofacial Research – volume: 5 start-page: 112 year: 2003 end-page: 123 article-title: Space‐providing expanded polytetrafluoroethylene devices define alveolar augmentation at dental implants induced by recombinant human bone morphogenetic protein 2 publication-title: Clinical Implant Dentistry and Related Research – volume: 17 start-page: 124 year: 1997 end-page: 139 article-title: A feasibility study evaluating rhBMP‐2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation publication-title: International Journal of Periodontics and Restorative Dentistry – ident: e_1_2_14_22_1 doi: 10.1111/j.1601-6343.2009.01461.x – volume: 32 start-page: 61 year: 2012 ident: e_1_2_14_14_1 article-title: The negative effect of combining rhBMP‐2 and Bio‐Oss on bone formation for maxillary sinus augmentation publication-title: International Journal of Periodontics and Restorative Dentistry – ident: e_1_2_14_2_1 doi: 10.1016/j.joms.2005.08.018 – ident: e_1_2_14_9_1 doi: 10.1016/j.joms.2007.11.021 – ident: e_1_2_14_11_1 doi: 10.1902/jop.1997.68.12.1186 – ident: e_1_2_14_10_1 doi: 10.1016/j.joms.2007.06.670 – ident: e_1_2_14_18_1 doi: 10.1007/s00264-007-0418-6 – ident: e_1_2_14_5_1 doi: 10.1902/jop.2000.71.8.1241 – ident: e_1_2_14_15_1 doi: 10.1902/jop.2012.110369 – ident: e_1_2_14_21_1 doi: 10.1016/j.joms.2009.04.085 – volume: 16 year: 2009 ident: e_1_2_14_7_1 article-title: Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment publication-title: Cochrane Database Systematic Review doi: 10.1002/14651858.CD003878.pub4 – ident: e_1_2_14_3_1 doi: 10.1016/j.joms.2005.08.018 – ident: e_1_2_14_13_1 doi: 10.1111/j.1600-0501.2008.01648.x – ident: e_1_2_14_8_1 doi: 10.1902/jop.2005.76.4.605 – volume: 7 year: 2009 ident: e_1_2_14_6_1 article-title: Interventions for replacing missing 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To compare the effect of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft... View the pubcast on this paper at http://www.scivee.tv/journalnode/60739 To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for... Aim To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft... |
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| SubjectTerms | Absorbable Implants Adult Alveolar Process - diagnostic imaging alveolar ridge augmentation Alveolar Ridge Augmentation - methods Atrophy autogenous bone graft Autografts - transplantation Biocompatible Materials - chemistry Bone Morphogenetic Protein 2 - therapeutic use Bone Transplantation - methods Clinical trials Collagen Cone-Beam Computed Tomography - methods Dental Implantation, Endosseous - methods Dental Implants Dentistry Drug Carriers Female Follow-Up Studies Humans Jaw, Edentulous, Partially - diagnostic imaging Jaw, Edentulous, Partially - surgery Male Maxilla - diagnostic imaging Maxilla - surgery Middle Aged Osteogenesis - physiology randomized-controlled trial recombinant human bone morphogenetic protein Recombinant Proteins - therapeutic use rhBMP-2 Surgical Mesh Titanium - chemistry Transforming Growth Factor beta - therapeutic use Transplants & implants |
| Title | Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial |
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